Brain Metastases Flashcards

1
Q

Brain metastases

A
  • secondary brain tumours
  • originate from malignant neoplasms elsewhere in body
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2
Q

Most frequent primary sites of brain metastases

A
  • lung
  • breast
  • melanoa
  • renal
  • colorectal
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3
Q

Pathophysiology of brain metastases

A
  1. haematogenous spread of cancer cells from primary tumour
  2. cells adhere to capillary endothelium of BBB
  3. cells move into brain and parenchyma
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