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Pathology I > P9 - Inflammation Part 4 > Flashcards

P9 - Inflammation Part 4 Flashcards

1
Q

exudate is part of

A
  • active part of inflammation
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2
Q

exudate components (3)

A
  • fluid component
  • cellular component
  • chemical component
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3
Q

fluid component of exudate

A
  • medium for cells, nutrients and other factors
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4
Q

cellular component of exudate

A
  • granulocytes and mononuclear cells
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5
Q

chemical component of exudate

A
  • factors that drive and regulate inflammation
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6
Q

transudate is part of

A
  • passive congestion
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7
Q

transudate and exudate effect on vascular permeability

A
  • exudate -> increased

- transudate -> no change

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8
Q

transudate and exudate protein content

A
  • transudate - low

- exudate - 2.5-3

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9
Q

transudate and exudate cells

A
  • transudate - rare cells present

- exudate - high number of inflammatory cells

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10
Q

exudate categorized based on timeframe

A
  • acute ( <10 days)

- chronic ( >10 days)

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11
Q

types of acute exudate (5)

A
  • serous
  • serohemorrhagic
  • fibrinous
  • catarrhal
  • purulent
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12
Q

types of chronic exudate (2)

A
  • granulomatous

- lymphoplasmacytic

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13
Q

exudate that is composed of blood plasma with very few cells

  • often seen in cavities, skin, lungs and mucosal surfaces
  • high in protein
  • changes in vascular permeability
  • very few inflammatory cells
A

serous

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14
Q

exudate that is a result of vascular damage or widespread diapedesis that red tinged

A

serohemorrhagic

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15
Q

benefit of serous and serohemorrhagic exudate (2)

A
  • dilute bacteria

- increase nutrients that tissue needs

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16
Q

cost of serous and serohemorrhagic exudate

A
  • problematic when fills cavities on in respiratory tract
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17
Q

fibrinogen escapes vasculature and is converted to

A
  • fibrin
18
Q

pseudomembrane associate with fibrinous exudate

A
  • mat of fibrin that can be pulled off

- epithelium stay in tact

19
Q

diphtheritic membrane associated with fibrinous exudate

A
  • pulling off mat results in ulceration

- epithelium is pulled off

20
Q

fibrin cast associated with fibrinous exudate

A
  • fibrin discharged from organ as single hard structure
21
Q

benefit of fibrinous exudate

A
  • layer of protection

- pathogen entrapment

22
Q

cost of fibrinous exudate

A
  • impede absorption

- can form adhesions restricting function and movement of organs

23
Q

prolonged fibrinous exudate becomes framework for

A

fibrous connective tissue

- cannot be pulled off

24
Q

exudate that is mucous cell hyperplasia

A

catarrhal

25
Q

benefit of catarrhal exudate

A
  • immunity (entraps bacteria and pathogens)
  • protect mucosal surface from damage
  • contains inflammatory factors and flushes foreign material
26
Q

cost of catarrhal exudate

A
  • can be hard to clear
27
Q

neutrophilic exudate

A

purulent

28
Q

empyema

A
  • pus filled body cavities
29
Q

type of necrosis associated with purulent exudate

A
  • liquefactive
30
Q

benefit of purulent exudate

A
  • highly effective

- non-specific method of neutralizing many etiologies

31
Q

costs of purulent exudate

A
  • can cause passive destruction of host tissue
32
Q

exudate that is predominately epitheloid macrophages with fewer lympocytes and plasma cells

A
  • granulomatous
33
Q

gross appearance of granulomatous exudate

A
  • enlarged
  • firm
  • pale
34
Q

granuloma

A
  • type of granulomatous inflammation

- distinct aggregates of macrophages that wall off inciting cause

35
Q

benefit of granulomatous exudate

A
  • robust mechanism to eliminate or sequester inciting cause
36
Q

cost of granulomatous exudate

A
  • body is beginning to concede that containment may be best option
37
Q

exudate with mix of lymphocytes and plasma cells often in typical areas

A
  • lymphoplasmactic
38
Q

benefit of lymphoplasmactic exudate

A
  • inclusion of adaptive immunity in inflammatory response
39
Q

cost of lymphoplasmactic exudate

A
  • extensive inflammatory infiltrates likely contribute to organ dysfunction
40
Q

mixed inflammatory infiltrates

A
  • dynamic and continuous

- more than 1 inflammatory process may be occurring

Pathology I (42 decks)

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