P13 - Neoplasia Flashcards
1
Q
hyperplasia
A
- increase in cellular numbers
2
Q
is hyperplasia reversible
A
- yes
3
Q
epithelial cells ability to undergo hyperplasia
A
- quick to respond to stimuli for proliferation
4
Q
smooth muscle, bone and cartilage ability to undergo hyperplasia
A
- intermediate ability to proliferate
5
Q
striated muscle, nervous system ability to undergo hyperplasia
A
- negligible
6
Q
physiologic causes of hyperplasia
A
- endometrial and mammary gland epithelial cells to hormones
7
Q
compensatory causes of hyperplasia
A
- damage to one part of an organ
- wound healing
- goiter
8
Q
goiter
A
- thyroid gland undergo hyperplasia in response to iodine deficiency
9
Q
pathologic causes of hyperplasia
A
- persistent stimulation
- can be precursor to neoplastic transformation
10
Q
idiopathic causes of hyperplasia
A
- nodular hyperplasia rather common in certain organs such as liver, pancreas or spleen
11
Q
metaplasia
A
- transformation of one differentiated cell type to another
12
Q
dysplasia
A
- abnormal pattern of tissue growth, often with disorderly arrangement of cells and cell atypia
13
Q
dysplasia is often due to
A
- persistent, severe injury/irritation
14
Q
anaplasia
A
- loss of cellular differentiation
15
Q
primitive cellular morphology
A
- variation in size and shape
- nuclear variability
- prominent and hyperchromic nucleoli
- mitotic figures