P40 - Integumentary Part 2 Flashcards
spongiosis
- intercellular edema of epidermis
- common with epidermal inflammation
hydropic degeneration and what is it common to occur with
- keratinocyte swelling limited to basal keratinocyte layer
- occurs with lupus erythematosus; dermatomyositis; drug eruptions
ballooning degeneration
- keratinocyte swelling within multiple layers
- common with viruses
vesicles
- fluid-filled spaces within or beneath epidermis (blisters)
bulla
- large vesicles > 1cm
acanthoylsis
- disruption of intracellular junctions (desmosomes) between keratinocytes of epidermis
acanthoylsis can be caused by
- immune-mediated injury (type II cytotoxic hypersnesitivity)
pemphigus foliaceus acanthoylsis location
- superficial epidermis
- subcorneal pustules
pemphigus vulgaris acanthoylsis location
- deep epidermis
- suprabasilar vesicles and clefts with tombstoning and ulceration
epidermitis is commonly accompanied by
- spongiosis
pigmentary incontinence
- histological feature which refers to loss of melanin by damage to stratum basale with resulting accumulation of melanin within macrophages in superficial dermis
dermal atrophy; common in
- decrease in quantity of collagen and fibroblasts in dermis
- cushing’s
collagen dysplasia results in
- increased stretchability of skin
abnormal deposits in the dermis (3)
- amyloid
- mucin - Shar-pei
- calcium
mucin accumulation in skin is called
- cutaneous myxedema
calcium deposits in dermis 3 forms
- dystrophic - hyperadrenocorticism
- metastatic - in tissues during hypercalcemia
- idiopathic - unknown cause
calcinosis circumscripta is what kind of syndrome
- syndrome of dermal calcification that typically occurs over pressure points
4 outcomes of acute dermatitis
- complete resolution
- formation of an abscess (pyoderma)
- healing and replacement by scar tissue
- progression to chronic dermatitis
causes of chronic dermatitis (4)
- persistent infections
- granulomatous conditions
- autoimmune dermatitis
- sustained physical injury or self-trauma
hypertrophy of andexa can be caused by (3)
- acral lick dermatitis
- chronic allergic dermatitis
- chronic bacterial and yeast infections
color dilution follicular dysplasia
- mutant color alopecia
- causes clumping of melanin pigment and increased hair shaft fragility
atrophic follicular dysplasia
- pattern baldness
cyclic follicular dysplasia
- seasonal alopecia
mural folliculitis
- inflammation of hair follicle wall
- seen with demodex
luminal folliculitis
- inflammation of follicle lumen
bulbitis
- inflammation of bulb (alopecia areata)
furunculosis
- severe luminal folliculitis that can lead to distention of hair follicle by exudate
furunculosis can lead to
- nodular skin mass and localized bacterial infection
breed predilections of sebaceous adenitis
- poodles
- akita
- samyoid
- visla
sebaceous adenitis causes
- dry flaky hair and skin
hidradenitis
- inflammation of apocrine gland
