P40 - Integumentary Part 2

Question 1

spongiosis

Answer 1

• intercellular edema of epidermis

- common with epidermal inflammation

Question 2

hydropic degeneration and what is it common to occur with

Answer 2

• keratinocyte swelling limited to basal keratinocyte layer

- occurs with lupus erythematosus; dermatomyositis; drug eruptions

Question 3

ballooning degeneration

Answer 3

• keratinocyte swelling within multiple layers

- common with viruses

Question 4

vesicles

Answer 4

• fluid-filled spaces within or beneath epidermis (blisters)

Question 5

bulla

Answer 5

• large vesicles > 1cm

Question 6

acanthoylsis

Answer 6

• disruption of intracellular junctions (desmosomes) between keratinocytes of epidermis

Question 7

acanthoylsis can be caused by

Answer 7

• immune-mediated injury (type II cytotoxic hypersnesitivity)

Question 8

pemphigus foliaceus acanthoylsis location

Answer 8

• superficial epidermis

- subcorneal pustules

Question 9

pemphigus vulgaris acanthoylsis location

Answer 9

• deep epidermis

- suprabasilar vesicles and clefts with tombstoning and ulceration

Question 10

epidermitis is commonly accompanied by

Answer 10

• spongiosis

Question 11

pigmentary incontinence

Answer 11

• histological feature which refers to loss of melanin by damage to stratum basale with resulting accumulation of melanin within macrophages in superficial dermis

Question 12

dermal atrophy; common in

Answer 12

• decrease in quantity of collagen and fibroblasts in dermis
• cushing’s

Question 13

collagen dysplasia results in

Answer 13

• increased stretchability of skin

Question 14

abnormal deposits in the dermis (3)

Answer 14

• amyloid
• mucin - Shar-pei
• calcium

Question 15

mucin accumulation in skin is called

Answer 15

• cutaneous myxedema

Question 16

calcium deposits in dermis 3 forms

Answer 16

• dystrophic - hyperadrenocorticism
• metastatic - in tissues during hypercalcemia
• idiopathic - unknown cause

Question 17

calcinosis circumscripta is what kind of syndrome

Answer 17

• syndrome of dermal calcification that typically occurs over pressure points

Question 18

4 outcomes of acute dermatitis

Answer 18

• complete resolution
• formation of an abscess (pyoderma)
• healing and replacement by scar tissue
• progression to chronic dermatitis

Question 19

causes of chronic dermatitis (4)

Answer 19

• persistent infections
• granulomatous conditions
• autoimmune dermatitis
• sustained physical injury or self-trauma

Question 20

hypertrophy of andexa can be caused by (3)

Answer 20

• acral lick dermatitis
• chronic allergic dermatitis
• chronic bacterial and yeast infections

Question 21

color dilution follicular dysplasia

Answer 21

• mutant color alopecia

- causes clumping of melanin pigment and increased hair shaft fragility

Question 22

atrophic follicular dysplasia

Answer 22

• pattern baldness

Question 23

cyclic follicular dysplasia

Answer 23

• seasonal alopecia

Question 24

mural folliculitis

Answer 24

• inflammation of hair follicle wall

- seen with demodex

Question 25

luminal folliculitis

Answer 25

• inflammation of follicle lumen

Question 26

bulbitis

Answer 26

• inflammation of bulb (alopecia areata)

Question 27

furunculosis

Answer 27

• severe luminal folliculitis that can lead to distention of hair follicle by exudate

Question 28

furunculosis can lead to

Answer 28

• nodular skin mass and localized bacterial infection

Question 29

breed predilections of sebaceous adenitis

Answer 29

• poodles
• akita
• samyoid
• visla

Question 30

sebaceous adenitis causes

Answer 30

• dry flaky hair and skin

Question 31

hidradenitis

Answer 31

• inflammation of apocrine gland