P29 - Hepatobiliary and Exocrine Pancreas Part 3 Flashcards
numerous systemic viral infections cause what most common acute liver lesions
- acute multifocal hepatocellular necorsis
liver abcessation and granulomas is most common in
- neonatal foals, ruminants and feedlot cattle
- due to bacteria
tyzzer’s disease caused by and is most common in
- clostridium piliforme
- foals
leprospirosis caused by
- leptospira interrogans
protozal and fungal infections of liver are by ____ spread
- hematogenous spread
milk-spotted liver is due to
- Ascaris suum migration in pigs
fasciola magna infection in aberrant host (cattle/sheep) results in
- more extensive hepatic injury and necrosis with eventual death
heterobilharzia americana results in what damage to the liver
- severe granulomatous inflammation of liver
what organ is subject to toxicity more than any other organ
- liver
most common response of hepatotoxic injury
- centrilobular necrosis
centrilobular hepatocytes contain highest concentration of
cytochrome p450 enzymes
gross appearance of liver with blue-green algae hepatotoxicity
- hemorrhagic gastroenteritis and red, swollen, necrohemorrhagic liver with massive lobular necrosis -> acute liver failure
gross lesion of pyrrolizidine alkaloid-containing plants ingestion
- diffuse hepatic fibrosis and biliary hyperplasia with variable nodular regeneration
histologic lesion of pyrrolizidine alkaloid-containing plants
- hepatocellular necrosis and formation of enlarged hepatocytes
most important source of aflatoxin
- aspergillus flavus
