P46 - Integumentary Part 8 Flashcards

1
Q

4 categories of genes affected for neoplastic transformation

A
  • tumor-suppressor genes
  • proto-oncogenes
  • genes that regulate apoptosis
  • genes that regulate DNA repair
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2
Q

hallmark feature of malignancy

A
  • metastasis
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3
Q

nailbed keratoacanthoma generally presents as

A
  • swollen digit
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4
Q

nailbed squamous cell carcinoma is a

A
  • destructive tumor with invasion of phalangeal bone and metastasis to regional lymph nodes and/or lungs
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5
Q

what is the frequent site of metastasis for pulmonary cancer in cats

A
  • digits
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6
Q

sebaceous gland of eyelids is common in what species

A
  • dogs
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7
Q

what is the most common apocrine gland tumor and what is it associated with

A
  • anal sac gland adenoma/adenocarcinoma

- associated with hypercalcemia

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8
Q

canine nodular dermatofibrosis is common in what species

A
  • german shepherds
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9
Q

feline vaccine-associated sarcoma is what type of tumor

A
  • fibrosarcoma
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10
Q

malignant spindle cell tumor that is the most common cutaneous neoplasm in horses

A
  • sarcoid
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11
Q

common malignant spindle cell tumor in dogs

A
  • hemangioperiytoma
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12
Q

liposarcoma

A
  • malignant lipocytic tumor
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13
Q

where are melanomas located that usually mean they are malignant

A
  • nailbed, mucocutaneous junctions, oral cavity
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