P39 - Integumentary Flashcards

1
Q

atpoic dermatopathy vs. atrophic dermatopathy

A
  • atopic - allergic skin disease

- atrophic - atrophy

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2
Q

epidermis layers (4)

A
  • stratum corneum
  • stratum granulosum
  • stratum spinosum
  • stratum basale
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3
Q

which layer of epidermis has melanocytes, langerhans cells and merkel cells

A
  • stratum basale
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4
Q

desmosomes

A
  • provide intercellular adhesion between keratinocytes
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5
Q

hemidesmosomes

A
  • provide attachment of epidermis to basement membranes
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6
Q

adnexa is also known as

A
  • hair follicles
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7
Q

cycle of hair growth (4)

A
  • anagen - growth period
  • catagen - transition period
  • telogen - resting period
  • exogen - shedding period
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8
Q

what is hair growth affected by

A
  • photoperiod

- nutrition and health status

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9
Q

what is the most important barrier against infection and fluid loss of the skin

A
  • stratum corneum
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10
Q

Langerhans cells are part of what type of immunity

A
  • adaptive

- produce pro-inflammatory cytokines

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11
Q

regeneration and repair of skin injury (7)

A
  • blood clotting
  • inflammation
  • re-epithelialization
  • fibroplasia
  • angiogenesis
  • wound contraction
  • tissue remodeling
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12
Q

what is a hallmark histologic feature of healing

A
  • granulation tissue
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13
Q

ichthyosis

A
  • fish like disease
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14
Q

hereditary hyperkeratosis is common in what breed

A
  • labrador retreiver
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15
Q

cornification

A
  • transformation of squamous epithelial cells into keratin layer of stratum corneum, hair, nails
  • forming thin layers of keratin
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16
Q

hyperkeratosis

A
  • flaky and scaly skin
17
Q

nutritional disorder (vit A deficiency) can result is what kind of skin disorder

A
  • secondary (acquired) cornification disorder
18
Q

epidermal hyperplasia (acanthosis)

A
  • diffuse thickening of epidermis with increased number of keratinocytes
19
Q

apoptosis of epidermis to injury usually results from what immune-mediated disorders (2)

A
  • lupus erythematosus

- erythema multiforme

20
Q

atrophy of skin is commonly seen with ____ in dogs

A
  • Cushing’s
21
Q

main responses of epidermis to injury (4)

A
  • growth and differentiation
  • fluid balance and cellular adhesion
  • inflammation
  • alteration in pigmentation