P39 - Integumentary Flashcards
atpoic dermatopathy vs. atrophic dermatopathy
- atopic - allergic skin disease
- atrophic - atrophy
epidermis layers (4)
- stratum corneum
- stratum granulosum
- stratum spinosum
- stratum basale
which layer of epidermis has melanocytes, langerhans cells and merkel cells
- stratum basale
desmosomes
- provide intercellular adhesion between keratinocytes
hemidesmosomes
- provide attachment of epidermis to basement membranes
adnexa is also known as
- hair follicles
cycle of hair growth (4)
- anagen - growth period
- catagen - transition period
- telogen - resting period
- exogen - shedding period
what is hair growth affected by
- photoperiod
- nutrition and health status
what is the most important barrier against infection and fluid loss of the skin
- stratum corneum
Langerhans cells are part of what type of immunity
- adaptive
- produce pro-inflammatory cytokines
regeneration and repair of skin injury (7)
- blood clotting
- inflammation
- re-epithelialization
- fibroplasia
- angiogenesis
- wound contraction
- tissue remodeling
what is a hallmark histologic feature of healing
- granulation tissue
ichthyosis
- fish like disease
hereditary hyperkeratosis is common in what breed
- labrador retreiver
cornification
- transformation of squamous epithelial cells into keratin layer of stratum corneum, hair, nails
- forming thin layers of keratin
hyperkeratosis
- flaky and scaly skin
nutritional disorder (vit A deficiency) can result is what kind of skin disorder
- secondary (acquired) cornification disorder
epidermal hyperplasia (acanthosis)
- diffuse thickening of epidermis with increased number of keratinocytes
apoptosis of epidermis to injury usually results from what immune-mediated disorders (2)
- lupus erythematosus
- erythema multiforme
atrophy of skin is commonly seen with ____ in dogs
- Cushing’s
main responses of epidermis to injury (4)
- growth and differentiation
- fluid balance and cellular adhesion
- inflammation
- alteration in pigmentation
