module 9: IBD

Question 1

IBD: Crohn’s- chronic inflammatory disorder that has periods of ___ and ____
affects any part of the GI tract from ___to ___, but most often in the ____ and ____

Answer 1

remission and exacerbation

mouth to anus, more in the ileum and proximal colon

Question 2

IBD: Crohn’s risk factors
___,___hx,___descent, age, altered _____
^risk of ___CA

Answer 2

smoking, fam hx, jewish, <40, altered gut biome

Question 3

IBD: Crohn’s associated with ___ gene mutation (impaired)

which is responsible for recognizing ____ in the intestinal ___cells

Answer 3

CARD15/NOD2

recognizing bacteria in intestinal epithelial cells

Question 4

IBD: Crohn’s associated with ___involvement of affected area
___lesions
may progress to ____formation in the GI tract

Answer 4

transmural
skip lesions
abscess formation

Question 5

IBD: Crohn’s causes

4

Answer 5

infection,
impaired Cell immunity
autoimmune,
psychosomatic

Question 6

IBD: Crohn’s s/s

Answer 6

abd pain, diarrhea, dehydration, bloody stools, malabsorption, malnutrition (vB12/D/Ca/folic acid), weight loss,
obstruction, fistulas, perforation,
strictures=obstruction

Question 7

IBD: Ulcerative colitis- inflammatory disease of ___intestine, ^in ___ and ____colon
only affects ___and not ____intestine
ulcerations are ____
has periods of ____ and ____

Answer 7

large intestine, more in rectum and sigmoid colon
only affects colon and not small intestine
ulcerations are superficial
remission and exacerbation

Question 8

IBD: ulcerative colitis less common in ___
same sx’s but no ___, may have ___
will have chronic, recurring _____

Answer 8

smokers
no malabsorption, may have fevers
bloody diarrhea

Question 9

IBD: ulcerative colitis also experience

PUSEP

Answer 9

polyarthritis
uveitis 
sclerosing cholangitis 
erythema nodosum
pyoderma gangrenosum

Question 10

IBD: ulcerative colitis complications

FHPTCC

Answer 10

fissure,
hemorrhoids
perirectal abscess
toxic megacolon
colon perforation 
colorectal adenocarcinoma

Question 11

IBD: ulcerative colitis at increased risk for ___d/t chronic inflammation

Answer 11

VTE and microthrombi