Mod 3: Arachidonic acid pathway

Question 1

Arachidonic acid pathway responsible for synthesis of

Answer 1

prostaglandins

Question 2

What is responsible for the conversion of linoleic acid to arachidonic acid

Answer 2

Phospholipase A2

Question 3

arachidonic acid is converted to prostaglandin H2 by what

Answer 3

COX1 & COX2 enzymes

Question 4

Prostaglandin H2 undergoes further conversion to form

Answer 4

prostaglandins, thomboxane A2, prostacyclin

Question 5

Prostaglandins formed from COX1 pathway function to maintain

Answer 5

homeostasis

grastic mucosa, fluid/electrolyte balance, plt aggregation

Question 6

Prostaglandins from cox2 function in __ and __

Answer 6

inflammatory process, produce pain, fever

have role in homeostasis too: renal function, tissue repair, reproduction