Mod 7: mental and abnormalities Flashcards
Bipolar 1:
one ep of mania followed by depression
bipolar 2:
^women, major depression 2 weeks, hypomania 4 days
untreated= cv disease
loci on chromosome 18 and 22 linked to
bipolar, schizo
psychotic behavior w BP have deficits in
reelin expression , linked to chromosome 22 (schizo)
depression= ___ epi,norepi, dopamine, serotonin
increased w
decreased
mania
major depression has chronic ___ activation
HPA hypothalamic pituitary adrenal (cope w stress)
predictors of onset of depression
IL6, TNF
MD and BP have ___cerebral blood flow and ___metabolism
decreased, glucose metabolism in prefrontal cortex
spina bifida
vFolate, neural tube doesnt close
spinal cord/nerve roots malformed below lesion= loss of motor/sensory, autonomic function
anencephaly spina bifida
part of skull/brain missing, still born/die early
encephalocele spina bifida
brain and meninges sticks out of occipital skull defecrt
“cranial meningocele” if only meninges affected
meningocele spina bifida (mild)
sac w meninges, dont involve cord, no deficits
myelomeningocele spina bifida
meninges protrusion, spinal fluid/cord w nerves thru vertebra, most common, assc w hydrocephalus
located in lumbar area
cerebral palsy
disorder of movement, muscle tone, posture
cerebral palsy pyramidal
spastic, upper motor neuron damage
most common
rigid, ^dtr, scoliosis, contractures