Mod 5: CV hemodynamics

Question 1

Stroke volume dependent on _____

Answer 1

force of contraction

Question 2

Force of contraction dependent on ___

affected by stimulation of _____ agents

Answer 2

Preload that stretches ventricle

stimulation by positive/negative inotropic affects this

Question 3

Positive inotropic agents

Answer 3

epi/norepi

Question 4

negative inotropic agents

Answer 4

meds, cytokines, myocardial perfusion <50

Question 5

EF

Answer 5

% of blood ejected, stroke vol./end diastolic vol. 55-65%

Question 6

preload consists of
dependent on ___ and _______
^Preload can = __
affect on stroke volume

Answer 6

end diastolic vol. and end diastolic pressure
venous return and amt of blood left after systole
HF
vStroke volume and back up into pulm circ

Question 7

afterload

low = ____contraction , high= ____contraction

Answer 7

pressure the heart pushes against

low= faster contraction, high=slower contraction

Question 8

arterial blood pressure= ___ x____

Answer 8

CO x peripheral resistance

Question 9

MAP depends on ____ and ____

Answer 9

arterial elasticity and volume in arteries

Question 10

Pulse pressure directly related to _____ and ______

Answer 10

arterial stiffness and stroke volume

Question 11

adequate perfusion map=___ sbp=___

Answer 11

map=70, sbp=90

Question 12

peripheral (systemic) resistance directly r/t ____

Answer 12

diameter of arteries

Question 13

arterial diameter changes d/t \_\_\_\_ and
\_\_\_\_\_\_hormones (4) and
\_\_\_\_\_\_\_ hormones (2)

Answer 13

baroreceptors and vasoconstricting hormones (epi, norepi, angiotensin 2, vasopressin) and 
vasodilating hormones (natriuretic, neurodilantin)

Question 14

Calcium increases TENSION and CONTRACTION how

interacts w ____= ____moves= allows 2 to work together =_____

Answer 14

Ca+troponin C=tropomysosin moves=allows actin and myosin to work together to= contraction

Question 15

non-dihidropyridine Ca channel blockers (2)

dont give this to

Answer 15

Diltiazem and Verapamil

Systolic HF patients

Question 16

Catecholamine effect on contraction

Answer 16

catecholamines increase Ca pump activity= release from sarcoplasmic reticulum
increased

Question 17

vExtracellular Na effect on contraction

Answer 17

vNa/Ca exchanger activity = increased contraction

Question 18

Digitalis effect on contraction

Answer 18

blocks the Na/K pump = ^trapped Na
not enough extracellular Na for Na/Ca exchanger=^intra Ca=
increased contraction

Question 19

Beta blocker effect on contraction

Answer 19

blocks catecholamines = decreases contraction