Module 10: CKD

Question 1

How does CKD cause a loss of nephrons

Answer 1

injury= lose nephrons= remaining nephrons have ^glomerular filtration pressure (hyperfiltration)=fibrosis/scarring of nephrons =lose more nephrons

Question 2

CKD effects

Answer 2

uremia
anemia->Left Vent hypertrophy
fluid/electrolyte imbalance 
hyperparathyroid
htn
dyslipidemia 
vVitD Synthesis

Question 3

uremia with CKD

Answer 3

can cause AMS (BUN>100)

impaired plt function

Question 4

Hyperparathyroidism in ckd occurs to compensate for

causes osteoclastic activity can =

Answer 4

low calcium levels

osteodystrophy

Question 5

CKD can cause CV disease (Main cause of death) bc

Answer 5

dyslipidemia , htn d/t ^secretion of renin, anemia, vascular calcification

Question 6

CKD stage1

Answer 6

gfr>90ml/min

asymptomatic

Question 7

CKD stage 2

Answer 7

gfr 60-80ml/min

^PTH, subtle htn

Question 8

CKD stage 3

Answer 8

gfr 30-59ml/min

vErythropoietin, anemia, ^Cr/urea, mild htn

Question 9

CKD4

Answer 9

gfr 15-29

^triglycerides, metabolic acidosis, ^k, Na/h20 retention, ^BUN,Cr, ^phos, anemia, moderate htn

Question 10

CKD5

Answer 10

GFR<15, need HD=uremia, severe htn, anemia, ^Phos

Question 11

CKD renal structures damaged by 5 causes

Answer 11

DM
htn
glomerulonephritis 
polycystic kidney disease
obstructions (stones)