Mod 5: action potentials ekg Flashcards
ventricular action potentials phase 0 1 2 3 4
0-rapid depolarization (Na influx)
1-initial repolarization (na channels close, K leaves slow)
2- plateu (Ca influx {contraction} balances K efflux)
3-rapid repolarization (massive K efflux, Ca closes)
4-RMP -85mV (^k permeability)
Atrial action potentials
0
3
4
0-depolarize (open Ca)
3-repolarization (close Ca and open K)
4-slow depolarization (spontaneous Na influx)= automaticity
Adenosine and Acetylcholine effect on HR
vHR d/t vDepolarization rate
Catecholamines effect on heart rate
^HR d/t ^Depolarization rate
anti-arhythmic drugs class 1 2 3 4
- blocks sodium channels
- B-blocker
- prolongs AP by blocking K efflux
- Ca channel blocker
prolonged QT=^ risk for
ventricular arrhythmias
QRS=ventricular ____
depolarization
QT interval = ventricular
contraction
ST segment= ventricular
depolarization
U wave present in
bradycardia
Beta1
increase contractility, HR, renin
Beta2
vasodilation, bronchodilation
Alpha1
vasoconstriction
Dopamine
vasodilation
epi
B1
B2 AND a1, simultaneous stimulation= no change
^dose, a1 overrides B2
(^CO)