Mod 5: CAD, ACS Flashcards
Left anterior descending
anterior 2/3 intraventricular septum, papillary, ventrivle surface
left marginal artery
left ventricle, anterior
left circ
lateral and posterior walls of levt ventricle and atrium
rca
right atrium, both ventricles(^R)
r marginal
anter and posterior r ventricle
R posterior descending
posterior 1/3 interventricular septum
both ventricles posteriorly
post, medial papillary muscles
Right dominant if posterior descending rises from
L
R coronary artery
L circ
most commonly occuded
LAD
Rca
L circ
DM= CAD
thickening of ____ d/t
^___ and vProduction of
blood vessel walls d/t inflammation and leukocyte
^thrombosis and vProduction of nitric acid
leptin
adiponectin
^leptin= autoimmunity and vEndothelial angiogenesis
vAdiponectin=^CV risk (normally antiflammatory, ^nitric oxide pro`duction, attenuates ROS, v Smooth muscle production
CKD
^ calcification , ^G.F./s, dyslipidemia
NSAIDS
adverse effects on myocardial mitochondria
^ROS
plt aggregation, block aspirin
Prinzmetal angina
cp at rest, at night, d/t vasospasm with or without atherosclerosis
Nstemi
subendocardial infarct
st depression T wave inversion
>20 min
Stemi
permanent thrombus lodged
MI evolution decreased production of \_\_\_metabolism =vContracility \_\_\_ released=^afterload
vATP production anaerobic metabolism K, CA, mag lost=vContractiltiy reperfusion injury=cell death angiotensin 2 released= ^afterload/workload
(MI)
catecholamines released by
released by ischemic cells
norepi= vInsulin secretion= hyperglycemia 72hrs
myocardial stunning
contractility impaired hours-days d/ electrolyte imbalance and oxygen radicals
myocardial remodeling
neurohormonal process, hypertrophy, scarring, vContraction (like w HF)
hybernating myocardium
hypoxic tissues adapt until perfusion restored
trops
2-4 hrs of pain, 24hr peak, go away 7-10days
myocardial injury
st elevation/depression
myocardial infarction
q waves >25% of qrs complex height
v1-v4
LAD anterior wall
v1-v2
LAD anteroseptal
v4-v6
LAD anterolateral
I, aVL
Lcirc lateral wall
2, 3, aVF
RCA inferior wall