mod 8: dm Flashcards
Diagnostic criteria for DM (1 of these) A1c> fasting glucose 2 hour glucose tolerance sx's w random plasma glucose
aic > 6.5
fasting glucose >126
2 hour glucose tolerance >200
sx’s w random plasma glucose >200
Prediabetes
A1c
fasting glucose
2 hour glucose tolerance test
A1c 5.7-6.4
fasting glucose 100-125
2 hour glucose tolerance 140-199
Diabetes Type 1 A
what causes hyperglycemia
autoimmune destruction of pancreas beta cells= insulin not produced
hyperglycemia =80-90% are destroyed
Diabetes Type 1 A
low insulin = ^__secretion =
^___ and ____
^glucagon secretion =^glycogenolysis and gluconeogenesis
Diabetes Type 1 A
Autoimmune destruction of beta cells = decreased ___ secretion
decreased amylin secretion
Diabetes Type 1 A
metabolism of ___, ___, ___ is altered
fat, proteins, carbs
Diabetes Type 1 A
when glucose exceeds renal threshold=____
= ___,___,___
glucose spills into urine
=osmotic diuresis, polyuria, polydipsia
Diabetes Type 1 A
what leads to ketosis
lack of insulin, muscle/fat breakdown= weight loss
Diabetes Type 1 A
why do they experience polyphagia
depletion of carbs, fats, proteins