Module 10: female reproductive disorders Flashcards
cervical cancer risk factors
smoking, oral contraceptive use, immunodeficiency
High risk vs low risk HPV types
16 and 18 high risk
6 and 11 low risk
HPV causes precancerous dysplasia and ______
cervical carcinoma in situ
hpv s/s if present include ___,___,___
post coital vag bleeding, smelly discharge, abnormal uterine bleeding
Endometrial cancer (most common CA) risk factors:
obesity, early menses<12, late menopause>52, nulliparity, hx of breast/ovarian CA, tamoxifen use, xOvulation
Endometrial CA caused by
most are____
prolonged estrogen w no progesterone exposure
adenocarcinoma
Hallmark sign of endometrial CA
later sx
common site of mets
postmenopausal bleeding
can also have pain and vWeight later
lung
Ovarian CA (neoplasm, most deadly) risk factors
breast/colon/uterine CA fam hx, postmenopausal, infertile, early/late menses, genes, endometriosis, fertility drugs
Ovarian CA gene mutation in ___and___
and ___syndrome
BRCA1! and 2 supressor genes and tuners syndrome
Ovarian CA no early screening, vague sx that include (3)
when CA spreads intra abdominally over the peritoneum =(5)
vAppetite, abd distention, pelvic pain
pain, ascites, dispepsia, vomiting, BM changes
Breast CA (neoplastic) risk factors
early/late menses/menopause, oral BC, estrogen use, nulliparity, obese, atypical ductal hyperplasia/lobular hyperplasia, BRCA1,2, smoking, ^breast density, radiation to chest/breast during childhood
Most common site of Breast CA, common type___ and rise from ____
upper outer quadrant
adenocarcinoma and rise from carcinoma in situ
Breast CA sx
lump, nipple retraction, dimpling, swollen axillary nodes, nipple eczema/discharge