Lung Surfactant Flashcards
1
Q
Cell that produces SURFACTANT
A
Type II pneumocytes
2
Q
MAIN component of surfactant
A
WATER
3
Q
ACTIVE component of surfactant
A
Dipalmitoylphosphatidylcholine (DPPC)
4
Q
Mechanism for DPPC REDUCING SURFACE TENSION
A
Amphipathic Nature (Hydrophobic and Hydrophilic)
5
Q
Effect of SURFACTANT on lung COMPLIANCE
A
INCREASE
6
Q
START of sufactant PRODUCTION
A
24th week AOG
7
Q
MATURATION of SURFACTANT
A
35th week AOG
8
Q
TEST for SURFACTANT
A
Amniotic L:S ratio
N = 2.0 - 2.5
9
Q
Treatment for newborn RDS
A
steroids
surfactant
10
Q
LUNG SURFACTANT
A
Helps PREVENT ALVEOLAR COLLAPSE
Produced by TYPE II alveolar cells
Mixture of DPPC, other lipids and proteins
DECREASEDin the lungs of CHRONIC SMOKERS
