Lecture 21 - Mucoflagellates Flashcards

1
Q

T/F: mucoflagellates only reproduce asexually

A

TRUE

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2
Q

T/F: Mucoflagellates have indirect life cycles

A

FALSE

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3
Q

what is giardia duodenalis

A

species complex

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4
Q

how is giardia transmitted

A

fecal-oral

ingestion of cysts from feces, contaminated water, or fomites

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5
Q

what are the two stages of giardia

A
  1. trophozoite
  2. cysts
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6
Q

trophozoites are _____ but _____ while cysts are _____ and _____

A

active - noninfective
dormant - ineffective

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7
Q

what is the reproduction of trophozoites

A

binary fission

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8
Q

what is the pathogenesis of Giardia

A

indirect destruction of GI epithelial cells and villi

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9
Q

summarize the pathogenesis of giardia in

A
  1. trophozoites attach to small intestines
  2. damage to epithelial cells and enterocytes
  3. GI permeability and blunts intestinal villi
  4. reduced surface area
  5. maldigestion, malabsorption, hypersecretion
  6. D+
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10
Q

what are the clinical signs

A
  1. persistent diarrhea
  2. lethargy/weight loss
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11
Q

how is giardia diagnosed

A
  1. direct fecal
  2. fecal centrifuge
  3. antigen detection kits
  4. PCR
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12
Q

What is the recommended routine way to screen for giardia?

A

fecal float centrifugation

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13
Q
A
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