Lecture 21 - Mucoflagellates Flashcards
T/F: mucoflagellates only reproduce asexually
TRUE
T/F: Mucoflagellates have indirect life cycles
FALSE
what is giardia duodenalis
species complex
how is giardia transmitted
fecal-oral
ingestion of cysts from feces, contaminated water, or fomites
what are the two stages of giardia
- trophozoite
- cysts
trophozoites are _____ but _____ while cysts are _____ and _____
active - noninfective
dormant - ineffective
what is the reproduction of trophozoites
binary fission
what is the pathogenesis of Giardia
indirect destruction of GI epithelial cells and villi
summarize the pathogenesis of giardia in
- trophozoites attach to small intestines
- damage to epithelial cells and enterocytes
- GI permeability and blunts intestinal villi
- reduced surface area
- maldigestion, malabsorption, hypersecretion
- D+
what are the clinical signs
- persistent diarrhea
- lethargy/weight loss
how is giardia diagnosed
- direct fecal
- fecal centrifuge
- antigen detection kits
- PCR
What is the recommended routine way to screen for giardia?
fecal float centrifugation