Immunostimulants Flashcards
What are the Immunostimulants
Aldesleukin IFN Rituximab Cetuximab Infliximab Eternacept Abciximab Hyperimmune globins BCG vaccine Thalidomide
Recombinant IL-2
Aldesleukin
Anti CD20 Ab
Rituximab
Anti EGFR Ab
Cetuximab
Anti TNFalpha Ab
Infliximab
Eternacept
Anti GpIIb/IIIa Ab
Abciximab
Live attenuated vaccine against TB
BCG
When do you give IFN alpha
Kaposi’s sarcoma
Malignant melanoma
HBV
HCV
When do you give IFN beta
MS
When do you give IFN gamma
Chronic Granulomatous Disease
When do you give Rituximab
CD20+ tumors (NHL, CLL)
When do you give Cetuximab
Colorectal CA
What can cause Skin Rash and HS
Rituximab
Cetuximab
What are the Monoclonal Abs
Rituximab Cetuximab Infliximab Eternacept Abciximab
What do you give for RA
Infliximab
Eternacept
What prevents thrombus formation
Abciximab
When do you give Hyperimmune Globins
Tetanus Rabies Snake bites Digoxin OD Prevent HBV in newborns
What kind of immunity does Hyperimmune Globins confer
Passive
Who shouldn’t you give BCG to
Immunocompromised
What does Thalidomide do
Decreased TNFalpha
Enhance cell-mediated immunity
Anti-angiogenic effects
1st line Multiple Myeloma
Thalidomide
Thalidomide AE
Teratogenic Neuropathy Constipation DVT Sedation
