Immunostimulants Flashcards

1
Q

What are the Immunostimulants

A
Aldesleukin
IFN
Rituximab
Cetuximab
Infliximab
Eternacept
Abciximab
Hyperimmune globins
BCG vaccine
Thalidomide
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2
Q

Recombinant IL-2

A

Aldesleukin

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3
Q

Anti CD20 Ab

A

Rituximab

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4
Q

Anti EGFR Ab

A

Cetuximab

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5
Q

Anti TNFalpha Ab

A

Infliximab

Eternacept

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6
Q

Anti GpIIb/IIIa Ab

A

Abciximab

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7
Q

Live attenuated vaccine against TB

A

BCG

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8
Q

When do you give IFN alpha

A

Kaposi’s sarcoma
Malignant melanoma
HBV
HCV

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9
Q

When do you give IFN beta

A

MS

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10
Q

When do you give IFN gamma

A

Chronic Granulomatous Disease

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11
Q

When do you give Rituximab

A

CD20+ tumors (NHL, CLL)

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12
Q

When do you give Cetuximab

A

Colorectal CA

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13
Q

What can cause Skin Rash and HS

A

Rituximab

Cetuximab

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14
Q

What are the Monoclonal Abs

A
Rituximab
Cetuximab
Infliximab
Eternacept
Abciximab
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15
Q

What do you give for RA

A

Infliximab

Eternacept

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16
Q

What prevents thrombus formation

A

Abciximab

17
Q

When do you give Hyperimmune Globins

A
Tetanus
Rabies
Snake bites
Digoxin OD
Prevent HBV in newborns
18
Q

What kind of immunity does Hyperimmune Globins confer

A

Passive

19
Q

Who shouldn’t you give BCG to

A

Immunocompromised

20
Q

What does Thalidomide do

A

Decreased TNFalpha
Enhance cell-mediated immunity
Anti-angiogenic effects

21
Q

1st line Multiple Myeloma

A

Thalidomide

22
Q

Thalidomide AE

A
Teratogenic
Neuropathy
Constipation
DVT
Sedation