Anti-Microbial - General Info

Question 1

Antimicrobial

Answer 1

Inhibit growth microorganisms

Question 2

Antibacterial

Answer 2

Inhibit growth of bacteria

Question 3

Antibiotic

Answer 3

Inhibits microorganism growth and is made by other microorganisms

Question 4

Bacteriostatic

Answer 4

Reversible growth inhibition
Helps immune system remove it
Don’t give to immunocompromomised

Question 5

Bactericidal

Answer 5

Injure/Kill invading microorganism

Question 6

Post-Antibiotic effect

Answer 6

Killing action continues though drug plasma levels undetectable

Question 7

How does the Post-Antibiotic effect occur

Answer 7

Lag time for bacteria to synthesize new products
Persistence of agent at target site
Enhanced susceptibility host defenses

Question 8

Broad Spectrum

Answer 8

Works on several groups

Question 9

Narrow Spectrum

Answer 9

Few groups - Usually DOC

Question 10

Extended Spectrum

Answer 10

Gram+ and a few Gram-

Question 11

MBC

Answer 11

Lowest ABX conc to kill 99.9% of colony

Question 12

Empiric Therapy

Answer 12

Immediate therapy required

Don’t know what it is

Question 13

Example of Sequential Blockade

Answer 13

TMP + SMX

Question 14

Example of Blockade of Inactivating Enzymes

Answer 14

Clavulanic acid + Amoxicillin

Question 15

Example of Enhanced Drug Uptake

Answer 15

Aminoglycosides after Beta-lactams

Question 16

Resistance

Answer 16

Amount tolerable by host is innefective