GI drugs - Anti-emetic

Question 1

What are the 5-HT3 blockers

Answer 1

• Ondansetron
• Granisetron

Question 2

What is the NKI blocker

Answer 2

Aprepitant

Question 3

What are the corticosteroids

Answer 3

• Dexamethasone
• Methylprednisolone

Question 4

What are the H1 blockers

Answer 4

Diphenhydramine Meclizine Cyclizine

Question 5

What is the Anti-M

Answer 5

Scopolamine

Question 6

What are the D2 blockers

Answer 6

• Prochlorperazine
• Promethazine
• Droperidol

Question 7

What are the Benzos

Answer 7

• Lorazepam
• Alprazolam
• Diazepam

Question 8

What is the Cannabinoid

Answer 8

Dronabinol

Question 9

What is the DOC for emesis in motion sickness

Answer 9

Scopolamine

Question 10

What acts at the neurokinin I receptors to block substance P

Answer 10

Aprepitant

Question 11

What is given for moderate/severe emesis in chemo

Answer 11

Ondasetron Granisetron

Question 12

What is given for early/delayed emesis in chemo

Answer 12

Aprepitant

Question 13

What can you combine with ondasetron to augment effect

Answer 13

Corticosteroids

Question 14

What can give EPS

Answer 14

D2 blockers

Question 15

What is given for anticipatory N/V (still chemo-induced)

Answer 15

Benzos

Question 16

What other effects do benzos have (aside from anti-emetic)

Answer 16

Sedative Axiolytic Amnesic

Question 17

When do you give H1 blockers

Answer 17

Chemo emesis Motion sickness

Question 18

When do you give Dronabinol

Answer 18

Chemo emesis (central acting)

Question 19

What else do the D2 blockers block

Answer 19

M

Question 20

How are the 5-HT3 blockers administered

Answer 20

IV Oral prophylaxis

Question 21

How is Aprepitant administered

Answer 21

PO

Question 22

Aprepitant AE

Answer 22

Dizziness Fatigue Diarrhea P450 interactions

Question 23

What other AE do D2 blockers have (not EPS)

Answer 23

Hypotension