GI drugs - Anti-emetic Flashcards
What are the 5-HT3 blockers
- Ondansetron
- Granisetron
What is the NKI blocker
Aprepitant
What are the corticosteroids
- Dexamethasone
- Methylprednisolone
What are the H1 blockers
Diphenhydramine Meclizine Cyclizine
What is the Anti-M
Scopolamine
What are the D2 blockers
- Prochlorperazine
- Promethazine
- Droperidol
What are the Benzos
- Lorazepam
- Alprazolam
- Diazepam
What is the Cannabinoid
Dronabinol
What is the DOC for emesis in motion sickness
Scopolamine
What acts at the neurokinin I receptors to block substance P
Aprepitant
What is given for moderate/severe emesis in chemo
Ondasetron Granisetron
What is given for early/delayed emesis in chemo
Aprepitant
What can you combine with ondasetron to augment effect
Corticosteroids
What can give EPS
D2 blockers
What is given for anticipatory N/V (still chemo-induced)
Benzos
What other effects do benzos have (aside from anti-emetic)
Sedative Axiolytic Amnesic
When do you give H1 blockers
Chemo emesis Motion sickness
When do you give Dronabinol
Chemo emesis (central acting)
What else do the D2 blockers block
M
How are the 5-HT3 blockers administered
IV Oral prophylaxis
How is Aprepitant administered
PO
Aprepitant AE
Dizziness Fatigue Diarrhea P450 interactions
What other AE do D2 blockers have (not EPS)
Hypotension
