GI drugs - Laxatives Flashcards
What are the bulk forming drugs
Methylcellulose
Psyllium
Bran
What are the stool softeners
Docusate
Mineral Oil
Glycerine
What are the osmotic agents
Mg salts
Mg(OH)3
Lactulose
Polyethylene Glycol
What are the GI stimulants
Senna
Bisacodyl
Castor Oil
What is the Cl channel activator
Lubiprostone
What are the Opioid antagonists
Alvimopan
Methylnaltrexone
What distends the bowels to stimulate peristalsis
Bulk forming drugs
What do you give got hepatic encephalopathy
Lactulose
What is the Tx for opioid constipation
Senna and Docusate
How does Lactulose treat hepatic encephalopathy
Draws out NH3 to prevent hyperammonemia
Acidification of gut lumen traps NH4+
Where do bulk forming drugs come from
Fruits and Vegetables
What does taking bulk forming drugs require
High fluid intake
When do you not give bulk forming drugs
Opioid constipation
What do you combine stool softeners with for opioid constipation
GI Stimulant
How Osmotic Agents act
Draw water into lumen to stimulate motility