Hematology Book Flashcards

1
Q

**know normal lab values for CBC

A

RBC 3.8-5.03
hb: 10.2-13.4
hit: 31.7-39.8
WBC: 4.86-11.4
platelet: 203-367

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2
Q

** understand anemia well. including how it occurs, what we see in the labs, what do we do about it

A

anemia is decreased number of RBC, quantity of hbg, and volume of PRBC to below normal caused by loss/destruction or impaired/decreased rate of production
treat underlying cause/possible transfusion

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3
Q

** what are we looking for with MCH and MCV

A

MCH: mass/volume
MCV: size

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4
Q

**reticulocyte count

A

decrease production: decrease reticulocyte
blood loss: increase reticulocyte
normal:
- infant 2-6%
- adult .5-2.5%

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5
Q

** normal and abnormal values for WBC, RBC, platelets

A

powerpoint
- WBC: 4.5-11
- RBC: 3.5-5.5
- platelet: 150-420

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6
Q

** understand the 3 types of anemia (microcytic, normocytic, macrocytic)

A

microcytic: small, decreased MCV
normocytic: decreased production
macrocytic: lagre, vit b12/folate decreased

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7
Q

** Understand iron deficiency anemia. what are the most common causes, how can we treat it? what are the symtoms? early vs late?

A

most common anemia
microcytic
increase cow milk consumption in toddlers but could also be due to menorrhagia or GI bleeds. increase iron in foods or supplement with 2-5mg/kg/day, symptoms of iron supplement is N/V/C and dark stools. Early anemia is asymptomatic. late anemia has tachycardia, tachypnea, cardiomegaly, koilpokolosis, and enlarged tongue, with fatigue and irritability

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8
Q

SICKLE CELL
**understand how children get the disease, what does it mean for them? what complications can the disease cause? how do we treat it?

A

autosomal recessive, both parents need it, 25% per pregnancy. acute chest syndrome, lower respiratory tract illness, consolidation with defined edges, vaso occlusive crisis, spleen squestrioun, pain meds, O2, IV fluids, antibiotics

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9
Q

SICKLE CELL
** what things make a complication more likely to happen

A

hypoxia, stress, dehydration, temp extremes, infection

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10
Q

SICKLE CELL
** what is vaso occlusive crisis? s/s or this, treatment for it, what causes it, what might a care plan for this patient look like? nursing dx?

A

stasis of blood with clumping of cells
pain, fever, tissue engorgment, abdominal pain
pain meds, O2, IV fluid
causes it: hypoxia, stress, dehydration, temp extremes, infection
pain meds, IV fluids, o2
nursing dx: tissue perfusion, pain, fluid volume

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11
Q

SICKLE CELL
** acute chest what is it, what are the s/s, tx?

A

cut lower resp tract illness
infiltrate XR, fever, chest pain, tachypnea, decrease O2
pai. meds, ABX, O2, Iv fluids, blood transfusion

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12
Q

SICKLE CELL
** what are some emergencies that occur in sickle cell patients

A

splenic sequestration, aplastic crisis, vasooculsion crisis, acute chest syndrome

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13
Q

SICKLE CELL
** what do we worry about in sickle cell patients with fever

A

emergency 38.5<
infection and can lead to crisis

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14
Q

SICKLE CELL
** common medications

A

folic acid
penicillin
hydroxurea

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15
Q

SICKLE CELL
** review PCA use, who is it appropriate for, what considerations for families, what do we watch for or what complications might we be concerned about with PCA

A

+6yr and can self report pain
only child can press button
tolerance, resp depression

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16
Q

SICKLE CELL
** can sickle cell be cured? how? what are the risks

A

stem cell transplant
anemia, infection, bleeding, rejection

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17
Q

** what is hemophilia? what is the etiology? clinical manifestations? tx?

A

decrease clotting factor, X linked recessive disorder,
spontaneous bleeding, hemarthosis, ecchymosis, hematuria, intracranial bleeding
desmopressin, recomant factor VIII

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18
Q

erythropoesis

A

formation of RBC

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19
Q

polycythemia

A

above average number of RBC

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20
Q

leukopenia

A

decrease WBC

21
Q

thrombocytopenia

A

decrease platelet

22
Q

at birth hematopoiesis occurs in marrow of

A

nearly every bone

23
Q

once newborn begins breathing

A

RbC production slows

24
Q

WBC is higher at

A

birth

25
Q

platelet in newborn are lower than in

A

children and adult

26
Q

clotting factor is lower in

A

newborns

27
Q

what is the most common type of anemia

A

iron def

28
Q

iron def s/s are related to

A

degree

29
Q

mild - mod iron def s/s

A

asymptomatic

30
Q

severe s/s

A

fatigue
poor feeding
tachypnea
cardiomegaly
pica

31
Q

iron def hbg level

A

<11

32
Q

normocytuc anemia s/s

A

same as iron def but could have hepatomegaly and splenomegaly

33
Q

most common form of sickle cell

A

HBss

34
Q

thalassemias s/s

A

pallor
jaundice
growth retadation
hepatomegaly
splenomegaly

35
Q

cure for thalassemia

A

stem cell transplant

36
Q

deferoxamine

A

decrease iron due to transplants

37
Q

aplastic anemai

A

failure of bone marrow

38
Q

aplastic anemia s/s

A

petechie
purpura
epistasis
pallor

39
Q

aplastic anemia med

A

immunosuppressants
- cyclosporine

40
Q

aplastic anemia bone marrow

A

yellow and fatty

41
Q

hemophilia s/s

A

spontaneous bleeding
hemarthrosis
deep tissue hemorrhage
ecchymosis
hematuria

42
Q

hemophilia meds

A

desmopressin
recombinant VIII

43
Q

hemophilia disease carrying

A

X linked
- affected males
- female carriers

44
Q

most common hereditary bleeding disorder

A

von willebrand

45
Q

von willebrand s.s

A

prongloned and excessive mucotanous bleeding
brusing
expitasis
menorrhagia

46
Q

VW meds

A

infusion of von willebrand protein
desmopressin

47
Q

VW genetic

A

autosomal dominant

48
Q
A