Endocrine & Metabolic Book Flashcards

1
Q

GHD

A

decreased acitivty of pituitary gland
aka: hypopthyroidism
growth hormone is screted from anterior pit

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2
Q

GHD s/s

A

1 year old: 3% on growth
- normal at birth weight
hyponatremia
hypoglycmeia seizures
undecsenced testes
slipped carpital femoral epiphysis

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3
Q

GHD tx

A

growth hormone
- 6-7/wk subq
- administer at night
continuted until acceptable ht or growth velocity drops to less than 2cm, bone age over 14 year for girls for 16 for boys

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4
Q

GHD rf

A

hypothyroid
turners
cushings

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5
Q

precoucoius puberty

A

apperence of any 2ndary sexual characteristic
- 8y/o girls. 9y/o boys

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6
Q

thelarche

A

breast

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7
Q

menarhce

A

period

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8
Q

adrenarche

A

hair

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9
Q

precousious puberty

A

mood swings
emotional lability

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10
Q

XR on percousious puberty

A

advanced bone age
growth ceases premature, since homrones cause closure of epiphyseal plates

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11
Q

percousious puberty

A

GnRH analog
- tx continues until normal age of puberty is reached 11-12

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12
Q

education on percousious puberty

A

childs, social, cognitive, and emotional development is age

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13
Q

hypothyroidism

A

decrease thyroid hormone

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14
Q

hypothryroidism s/s

A

delayed growth
jaundice
thick tongue
hypotonia
hoarse cry
dry skin
goiter
cold
increase wt
decreased height velocity

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15
Q

hypothyroid labs

A

decreased t3/t4
increased tsh

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16
Q

hypothyroid tx

A

levo
- dose increase with age to ensure euthyroid = thyroid hormone in app balance

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17
Q

hyperthyroidism

A

increase thyroid hormone
graves

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18
Q

hyperthyroidism s/s

A

goiter
bluging eyes
eyelid lag
tachycardia
nervousness
increase app
wt loss
moodiness
hot

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19
Q

hyperthyroidism

A

T3/4 increase
TSH decrease

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20
Q

hyperthyroidism tx

A

methimazole
radiation
surgery

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21
Q

post op of hyperthyroidism surgery

A

always have calcium gluconate in case of decrease ca

22
Q

cushings

A

adrenalcortical hyperfunciton
pituitary hormone

23
Q

cushings

A

obesity
moon face
hypertension
hyperglycemia
buffalo hump

24
Q

cushings labs

A

increaed 24hr urinary levels of free cortisol and eleavte night time salviary cortisol level

25
Q

addisons disease

A

adrenal insuf

26
Q

addisons disease s/s

A

symptoms worsen with time
fatigue
wt loss
hypotension
salt craving
hypoglycemia

27
Q

addisons disease labs

A

measured in am

28
Q

addisons disease tx

A

hydrocortsone
steroids

29
Q

diabetes type1

A

hyperglyemia
- deficits of insulin secretion, action, both abnormalies of carbs, protein, fats
majority have T1

30
Q

T1 DM s/s

A

glycosuria: glucose in urine
polyuria
polydipsia
polyphagia

31
Q

T1 tx

A

insulin

32
Q

can long acting be mixed
- Glargine & determir

A

no

33
Q

carb counting

A

1U: 15g

34
Q

sick day rules

A

BS 2-3 hr
ketone 4 hr
contine insulin or inscrease

35
Q

cystic fibrosis RD

A

pancreas is scarred and doesnt produce enough insulin = deficiney
impairment of insulin = restiance

36
Q

honey moon phase

A

left over insulin production

37
Q

cause of DKA

A

incorrect insulin dose, missed dose, incorrect adminstraion, illness, trauma, surgery, new onset

38
Q

DKA how do we get ketones

A

adipose tissue releases fattu acids that convert to ketones

39
Q

DKA s/s

A

polyuria
polydipsia
N/V
dehydration
kussmaul
acetone breath
hypotension
hyperglycemia
glycosuria
ketonuria

40
Q

DKA what insulin

A

regular

41
Q

DM T2 s/s

A

acanthosis nigricans = hyperpigmentation and thickening of the skin

42
Q

DMT2 meds

A

meformin
sulfonurea
insulin

43
Q

turners

A

girls who have a missing or partial absence of one x chromosome

44
Q

turnerns s/s

A

short stature
inferility
webbed neck
low hairline
small jaw
low set ears
short fingers
broad chest
wide set nipples

45
Q

turners chromosome example

A

45X

46
Q

turner tx

A

growth hormone therapy

47
Q

klinefelter

A

boys who have an extra X chromosome

48
Q

klinefelter chromosone example

A

47XXY

49
Q

are turners and klinefelter infertile

A

yes

50
Q

klinefelter s/s

A

testes are small and firm
decrease hair
delayed milestone
decrease verbal IQ
difficulty with socializtaion
less muscular
broader hips
large brest

51
Q

klinefelter tx

A

tesosterone replacement at 11-12 years old