Endocrine & Metabolic Book Flashcards

1
Q

GHD

A

decreased acitivty of pituitary gland
aka: hypopthyroidism
growth hormone is screted from anterior pit

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2
Q

GHD s/s

A

1 year old: 3% on growth
- normal at birth weight
hyponatremia
hypoglycmeia seizures
undecsenced testes
slipped carpital femoral epiphysis

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3
Q

GHD tx

A

growth hormone
- 6-7/wk subq
- administer at night
continuted until acceptable ht or growth velocity drops to less than 2cm, bone age over 14 year for girls for 16 for boys

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4
Q

GHD rf

A

hypothyroid
turners
cushings

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5
Q

precoucoius puberty

A

apperence of any 2ndary sexual characteristic
- 8y/o girls. 9y/o boys

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6
Q

thelarche

A

breast

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7
Q

menarhce

A

period

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8
Q

adrenarche

A

hair

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9
Q

precousious puberty

A

mood swings
emotional lability

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10
Q

XR on percousious puberty

A

advanced bone age
growth ceases premature, since homrones cause closure of epiphyseal plates

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11
Q

percousious puberty

A

GnRH analog
- tx continues until normal age of puberty is reached 11-12

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12
Q

education on percousious puberty

A

childs, social, cognitive, and emotional development is age

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13
Q

hypothyroidism

A

decrease thyroid hormone

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14
Q

hypothryroidism s/s

A

delayed growth
jaundice
thick tongue
hypotonia
hoarse cry
dry skin
goiter
cold
increase wt
decreased height velocity

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15
Q

hypothyroid labs

A

decreased t3/t4
increased tsh

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16
Q

hypothyroid tx

A

levo
- dose increase with age to ensure euthyroid = thyroid hormone in app balance

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17
Q

hyperthyroidism

A

increase thyroid hormone
graves

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18
Q

hyperthyroidism s/s

A

goiter
bluging eyes
eyelid lag
tachycardia
nervousness
increase app
wt loss
moodiness
hot

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19
Q

hyperthyroidism

A

T3/4 increase
TSH decrease

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20
Q

hyperthyroidism tx

A

methimazole
radiation
surgery

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21
Q

post op of hyperthyroidism surgery

A

always have calcium gluconate in case of decrease ca

22
Q

cushings

A

adrenalcortical hyperfunciton
pituitary hormone

23
Q

cushings

A

obesity
moon face
hypertension
hyperglycemia
buffalo hump

24
Q

cushings labs

A

increaed 24hr urinary levels of free cortisol and eleavte night time salviary cortisol level

25
addisons disease
adrenal insuf
26
addisons disease s/s
symptoms worsen with time fatigue wt loss hypotension salt craving hypoglycemia
27
addisons disease labs
measured in am
28
addisons disease tx
hydrocortsone steroids
29
diabetes type1
hyperglyemia - deficits of insulin secretion, action, both abnormalies of carbs, protein, fats majority have T1
30
T1 DM s/s
glycosuria: glucose in urine polyuria polydipsia polyphagia
31
T1 tx
insulin
32
can long acting be mixed - Glargine & determir
no
33
carb counting
1U: 15g
34
sick day rules
BS 2-3 hr ketone 4 hr contine insulin or inscrease
35
cystic fibrosis RD
pancreas is scarred and doesnt produce enough insulin = deficiney impairment of insulin = restiance
36
honey moon phase
left over insulin production
37
cause of DKA
incorrect insulin dose, missed dose, incorrect adminstraion, illness, trauma, surgery, new onset
38
DKA how do we get ketones
adipose tissue releases fattu acids that convert to ketones
39
DKA s/s
polyuria polydipsia N/V dehydration kussmaul acetone breath hypotension hyperglycemia glycosuria ketonuria
40
DKA what insulin
regular
41
DM T2 s/s
acanthosis nigricans = hyperpigmentation and thickening of the skin
42
DMT2 meds
meformin sulfonurea insulin
43
turners
girls who have a missing or partial absence of one x chromosome
44
turnerns s/s
short stature inferility webbed neck low hairline small jaw low set ears short fingers broad chest wide set nipples
45
turners chromosome example
45X
46
turner tx
growth hormone therapy
47
klinefelter
boys who have an extra X chromosome
48
klinefelter chromosone example
47XXY
49
are turners and klinefelter infertile
yes
50
klinefelter s/s
testes are small and firm decrease hair delayed milestone decrease verbal IQ difficulty with socializtaion less muscular broader hips large brest
51
klinefelter tx
tesosterone replacement at 11-12 years old