Exam 3 part four Flashcards
Buffy coat in blood is?
Thin, slightly gray-white matter is composed of leukocytes & cell fragments (platelets). Forms less than 1% of a blood sample
Antibodies are
Molecules that can bind to antigens until a leukocyte can completely kill or remove the antigen, are transported in plasma.
What influence would high altitude living have on blood?
Because the air is thinner and there is less O2, each time they breath in, they inhale less O2 than they would at a lower altitude. Their body compensates by making more erythrocytes, more erythrocytes in the blood can carry more O2 to the tissues. This increase in erythrocytes results in an increased hematocrite
Hematocrit is
The percentage of the volume of all formed elements in the blood
Formed elements
3 components
1) Erythrocytes (99%). Transport respiratory gases in the blood
2) Leukocytes (<1%) Blood clotting
Erythrocytes are
RBC’s. Mature erythrocytes lack nuclei & organelles. Transport O2 & carbon dioxide to & from the tissues & the lungs. Biconcave disc allows respiratory gases to be loaded & unloaded rapidly.
Hemoglobin is
In RBC’s. Red pigmented protein. Transports O2 & carbon dioxide, red color. Has 4 polypeptide chains (globins). 2 called alpha, 2 called beta. Each chain has heme and iron in the center. O2 binds to iron
Bilirubin is
Yellow green pigment that biliverdin converts to. Component of a digestive secretion called bile, produced by liver cells.
Surface antigens
Molecules of the plasma membrane of an erythrocyte. Project from the plasma membrane surface. Most common group is the ABO blood group
Leukocytes
WBC that help initiate an immune response & defend the body against pathogens. Neutrophils, eosinophils, basophils, lymphocyte, monocyte
Platelets are
Thrombocytes. Continually produced in red bone marrow by megakaryocytes. Forms blood clots.
Hemocytoblasts are
Hemopoietic stem cells. Pluripotent cells (differentiate & develop into many diff. kinds of cells). Produce 2 lines for blood cell development: they myeloid & lymphoid.
Erythropoiesis is
Erythrocyte production. Begins with myeloid stem cell that forms a progenitor cell.
Thrombopoiesis is
The production of platelets
Leukopoiesis is
The production of leukocytes. Involves 3 diff. maturation processes: granulocyte maturation, monocyte maturation, lymphocyte maturation
Agglutination is
The clumping together of cells (such as bacteria and red blood cells) or particles
The ABO blood system is
classification of human blood based on the inherited properties of red blood cells (erythrocytes) as determined by the presence or absence of the antigens A and B, which are carried on the surface of the red cells. Persons may thus have type A, type B, type O, or type AB blooD
Why does an iron poor diet lead to anemia?
Because it is a condition in which the counts of erythrocytes is less than normal. Occurs due to inadequate production or decreased survival of erythrocytes. Without enough iron in your diet there isn’t anything for 02 to bind to in RBC’s without iron.
Fibrin net
Fibrinogen is activated to form fibrin nets & activated platelets can easily get caught to form a platelet plug
Platelet plug is
A platelet plug is a collection of sticky platelets that’s used to stop a wound from bleeding
Thrombocytes are
Platelets that function in blood clotting. Inactive platelets are smooth, but can become very irregular & sticky.
What is in the buffy coat?
WBC’s & platelets
O2 and Co2 in blood
Binds to hemoglobin in the RBC’s. O2 binds to iron in heme of hemoglobin.
Anemia is having a low _____ (diagnostic term?).
Hematocrite
The blood forming stem cell?
Hemocytoblast
Where is most of the O2 carried?
Heme (with Fe)
Describe RBC
Biconcave, hemoglobin containing, enucleate, round, O2 carrying, short lived
Which WBC becomes a macrophage?
Monoctye
What blood can Type A receive?
Type A or Type O
When does Rh cause a problem?
Mom is Rh-, baby is Rh+ and she has previously had an Rh+
When blood cells clump it is called?
Agglutination
Which pumps blood to the body (not lungs)?
Left ventricle
A contracting heart muscle is in _____? (phase of cardiac cycle?)
Systole
Action potentials in the heart are conducted along?
Intercalated discs
Pacemaker of the heart is?
SA node
Ascultation of the heart is listening for?
Valve sounds
Blood flow into capillaries is controlled by?
Precapillary sphincters
What is meant by the heart being a “double-pump”? Why?
Pulmonary & systemic circuits. Repressurize blood after oxygenating. Key term is “repressurize”
Arteries
Carry blood away from heart. Most carry blood in high O2 (except for pulmonary arteries)
Veins
Carry blood back to the heart. Most carry blood in low O2 (except for pulmonary veins)
Pulmonary circulation consists of
The chambers on the right side of the heart as well as the pulmonary arteries & veins. Conveys blood to the lungs via pulmonary arteries to reduce Co2 and replenish O2 levels in the blood before returning to the heart in pulmonary veins
Systemic circulation consists of
The chambers on the left side of the heart, along with all the other named blood vessels. Carries blood to all peripheral organs & tissues of the body.
Pericardial cavity is
Thin space between the parietal & visceral layers of the serous pericardium. Serous fluid is secreted to lubricate the serous membranes & facilitate the movement of the heart when it beats. Potential space with a thin lining of serous fluid.
Epicardium is
Outermost heart layer (visceral layer) of serous pericardium. Composed of a serous membrane & areolar connective tissue