Cáncer de Ovario: Generalidades Flashcards

1
Q

Epidemiología mundial

A
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2
Q

Epidemiología México

A

México
• 5193 nuevos casos por año
• 3360 muertes por año

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3
Q

FR

A

80% casos, >50 años
• BRCA1/2 (HBOC15%)
• Nulipardidad, menarca temprana, menopausia
tardia
• Obesidad

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4
Q

Orígenes Embrionarios

A

Células epiteliales
Células germinales (adolescentes y niñas)
Células del estroma

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5
Q

Variantes epitelioides

A
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6
Q

Deficiencia presente en el 50% de las px con cáncer de ovario

A

Deficiencia de la reparación homóloga

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7
Q

Síndromes predisposición

A

Sd susceptibilidad
BRCA
• Ca de mama y ovario

Síndrome deLynch (HNPCC)
• Colon, endometrio y ovario

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8
Q

Principal mecanismos que se busca atacar en deficiencias de recombinación homóloga

A

Letalidad sintética

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9
Q

Otros FR

A
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10
Q

Porcentaje de mujeres diagnosticadas en etapa avanzada

A

60%

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11
Q

Síntomas

A

Distensión abdominal
Cólicos más de 15 días
Edema
Dolor
Saciedad temprana
Dolor lumbar

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12
Q

Estadíos FIGO

A

Stage I: Cancer is limited to one or both ovaries.
Stage II: Cancer has spread to the uterus or other nearby organs.
Stage III: Cancer has spread to the lymph nodes or abdominal lining.
Stage IV: Cancer has spread to distant organs, such as the lungs or liver

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