3.5.3 Assisted Reproductive Treatments Flashcards
Describe the assisted reproductive technique of IVF and the indications of it.
IVF – in vitro fertilization, stimulate ovulation with hCG → US guided oocyte retrieval → IVF
Indications – tubal or pelvic factor, severe male infertility
What are the characteristics of egg cryopresentation?
![](https://s3.amazonaws.com/brainscape-prod/system/cm/212/684/660/a_image_thumb.png?1493406902)
What are the characteristics of rFSH stimulation?
![](https://s3.amazonaws.com/brainscape-prod/system/cm/212/684/359/a_image_thumb.png?1493406448)
What are the characteristics of Clomiphene citrate?
![](https://s3.amazonaws.com/brainscape-prod/system/cm/212/684/314/a_image_thumb.png?1493406381)
What are the main causes of infertility?
Male factor - 35%
Female - 50% - Tubal/pelvic path - 35%
Anovulation/oligoovulation -15%
What are some possible uterine anomalies?
Bicornuate
Didelphys
Unicornuate
Septate
T-shaped
What are the characteristics of IVF?
Requires careful monitoring
Risk of OHSS
Embryo transfer 5 days after retrieval
Can control number of embryos transferred
![](https://s3.amazonaws.com/brainscape-prod/system/cm/212/684/395/a_image_thumb.png?1493406490)
What is the risk for multiple gestation with Clomid and rFSH?
Clomid - 7% twins, 0.5% triplets
rFSH - 20% twins and 5% triplets
What are some possible causes of occluded fallopian tubes?
PID - particularily chlamydia
Endometriosis
If patient doesn’t want kiddos and has PCOS what are some treatment options?
OCPs, spironolactone, mirena IUD, provera,
What happens to the rate of fetal aneuploidy by maternal age?
![](https://s3.amazonaws.com/brainscape-prod/system/cm/212/684/549/a_image_thumb.png?1493406774)
What are teh important characteristics of oligospermia?
![](https://s3.amazonaws.com/brainscape-prod/system/cm/212/683/446/a_image_thumb.png?1493404961)
How does paternal age relate to fertility?
INcrease in spermatic DNA fragmentation but no increase in aneuploidy
Greater the 40 have greater risk of autism
What is the treatment of endometriosis?
If not wanting kids
Surgical fulguration/excision of endo
Menstrual suppression
If wanting kids - IVF if tubes are blocked, consider suppression prior to cycle w/ GnRH agonist
What is recurrent pregnancy loss?
2 or more sAB (clinical losses)