2.3.3 Pathology of the Ovaries II Flashcards
What is this an image of?
Mature cystic teratoma with malignant transformation
Struma ovarii
What are these images of?
Thyroid carcinoma in ovary tissue - struma ovarii
Type of teratoma
What are these images of?
Choriocarcinoma - some of these have hCG staining
What are the characteristics of Metastatic ovarian tumors?
Usually bilateral
Comes from the breast, colon or stomach
What are the characteristics of Fibroma?
Gorling Syndrome (basal cell nevus syndrome)
Meig’s syndrome - Large tumor, ascites, and pleural effusion
What are the microscopic findings associated with dysgerminoma?
Islands of uniform cells
Varying amys of CT stroma
Glycogen containing cytoplasm
What is this an image of?
Fibroma that had a little edema
What is this an image of?
Granulosa cell tumor
What are the characteristics of Choriocarcinoma?
hCG
What are the characteristics of a dysgerminoma (ovarian seminoma)
Most common malignant germ cell tumor of ovary
glycogen filled tumor
Younger age group (10-30)
What are the characteristics of Endodermal Sinus Tumor (Yolk Sac Tumor)?
Schiller-Duval Bodies
What is this an image of?
Yolk sac tumor - AFP immunostain
What is this an image of?
Sertoli-Leydig cell tumor
Characteristics Reinke Crystals
What is this an image of?
Granulosa cell tumor
Coffee-Bean nuclei
What is this an image of?
Cell-Exner body
Granulosa cell tumor
What is this an image of?
Choriocarcinoma
What are the characteristics of Mature Teratoma (Dermoid Cyst)?
Struma ovarii
What are the characteristics of a Thecoma?
Estrogen-secreting
Sex chord/stromal tumor
What are these images of?
Thecoma - oil Red O (Fat stain) on right
What is this an image of?
Dysgerminoma - ovarian seminoma
What are the characteristics of immature teratoma?
3 germ cell layers
Embyronal tissue - usually neural
Malignant, poor process
This is aggressive
What is this an image of?
Schiller-Duval body (Yolk Sac Tumor)
What are these images of?
Dermoid cyst
Can consist of bone, teeth, hair etc - due to the fact they are derived from germ cells
What are the Krukenburg tumors?
Adenocarcinoma, Mucin-Producing
Signet Ring Cells
Stomach, Colon, Breast
What are the characteristics of Granulosa cell tumors?
Estrogen secreting
Call-Exner Bodies
What is the pathology associated with Fibroma’s?
Gross - diffuse tan-white mass
Histology - fibroblasts
What are the characteristics of Sertoli-Leydig Cell tumors? (Arrhenoblastoma, androblastoma)
Androgen secreting
What is this an image of?
Thyroid tissue in dermoid cyst “struma ovarii”
What is this an image of?
Fibroma
Benign spindle cells
What are these images of?
Immature teratoma
