3.1.3 Breast Histology and Physiology Flashcards
What is this an image of?
TDLU atrophic ducts
What happens to the breast during pregnancy?
Describe the secretory function of mammary alveolar cells
What happens to the postmenopausal breast?
What happens to the breast after ovulation as a combined effect of estrogen and progesterone?
The number of acini per lobule increases
Vacuolization of epithelial cells
Marked intralobular stromal edema
What are the characteristics of Squamous metaplasia of lactiferous ducts (SMOLD)?
Not associated with lactation
Strong association with smoking
Squamous metaplasia of lactiferous ducts leads to keratin trapped within the duct and dilation leading to ruptur and an intense inflammatory response
Painful erythematous subareolar mass
Treated by surgical excision
What is this an image of?
Mammary duct ectasia
What is this an image of?
TDLU during pregnancy
What is the pathogenesis of Nonproliferative Fibrocystic changes?
Hormonal imbalances between estrogen and progesterone
What are the characteristics of intralobular stroma?
Loose, delicate myxomatous stroma
Hormonally responsive
Contains scattered lymphocytes
What is the most common presentation of breast cancer in the clinic?
Abnormal mammogram
What is this an image of?
Normal TDLU
What are the characteristics of nonproliferative fibrocystic changes in benign breast lesions?
Not a disease
Conferring no increased risk of developing carinoma
The single most common disorder of the breast
Palpable lumps, mammographic densities, calcifications and nipple discharges
What is this an image of?
Fat necrosis in the breast
What are the covered parts?