Brainscape's Knowledge GenomeTM

Browse over 1 million classes created by top students, professors, publishers, and experts.


See full index

Reproduction and Sexuality > 1.4.2 Testicular Neoplasia > Flashcards

1.4.2 Testicular Neoplasia Flashcards

1
Q

What type of therapy is used to treat testicular tumors?

A

Platinum based therapy

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
2
Q

What age group is responsible for 90% of testicular cancers?

A

20-50 y/o (if a tumor is found in the testis after the age of 50, it is probably a metastases

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
3
Q

How does a seminoma present?

A

Testicular enlargement or nodular mass that causes the patient dull pain or minor discomfort

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
4
Q

What is the most common type of germ cell tumor?

A

Seminoma (composed of one cell type)

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
5
Q

What type of tumor?

A

Leydig cell tumor

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
6
Q

What are the four types of germ cell testicular tumors?

A

Intratubular germ cell neoplasia (ITGCN), seminoma, nonseminomatous germ cell tumors, mixed seminoma

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
7
Q

Identify

A
How well did you know this?
1
Not at all
2
3
4
5
Perfectly
8
Q

Which cells are malignant? Describe their appearance

A

Fried egg appearance (precursor to germ cell tumor)

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
9
Q
A

1 C

2 C

3 B

4 B

5 D

6 D

7 C

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
10
Q

90% of tumors are from what type of cell?

A

Germ cells

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
11
Q

What type of tumor?

A

Sertoli cell tumor

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
12
Q

What this be?

A

Seminoma in a bisected testis

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
13
Q

What are the four different cell types that could give rise to testicular tumors?

A

Germ cells, Sertoli cells, Leydig cells, Stromal cells (rare)

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
14
Q

What is this?

A

Teratoma - embryonal carcinoma cells

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
15
Q

What is the cure rate in seminomas?

A

90%

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
16
Q

What are the two types of sex cord cell tumors (which accounts for 5% of testicular cancers)?

A

Leydig cell tumor, Sertoli cell tumor

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
17
Q

Identify A-E

A
18
Q

Identify the three regions

A
19
Q

What % of sex chord tumors are benign?

A

90%

20
Q

During the years of 25-50, where does testicular cancer rank among malignant cancers in men?

A

4th

21
Q

What are the common metastatic locations of germ cell tumors?

A

Paraaortic lymph nodes then solid organs (lung, brain, liver)

22
Q

Identify the two cell types in this seminoma

A

Top: tumor cells

Bottom: lymphocytes

23
Q

What is this?

A

Non-seminomatous germ cell tumor

24
Q

What is the most common type of sex chord tumor

A

Leydig > Sertoli

25
Q

What serologic marker is used to identify seminoma?

A

Trick question. There isn’t one

26
Q

What type of tumor is the yolk sac tumor?

A

childhood tumor (w/ AFP)

27
Q

What are the two serological markers of nonseminomatous germ cell tumor?

A

AFP and hCG

28
Q

Identify

A
29
Q

Which cells play a support function?

A

Sertoli cells and smooth muscle cells of the lamina propria

30
Q

What this be?

A

Seminoma (septa contain lymphocytes, tumor cells form lobules)

31
Q

Which cells secrete testosterone?

A

Leydig cells

32
Q

Identify the different cell types present

A
33
Q

What are the three risk factors for testicular germ cell tumors?

A

cryptochordism, gonadal dysgenesis, sex chromosome and genetic disorders

34
Q

What are the effects of leydig cell tumors in prepubertal children? Adults?

A

Prepubertal: precocious puberty, macrogenitosomia

Adults: gynecomastia

35
Q

What are the sex cord and germ cell tumors?

A
36
Q

What cell type?

A

Embryonal carcinoma cells

37
Q

What are the clinical features of a seminoma?

A
38
Q

What are the characteristics of Leydig cell tumor?

A
39
Q

Schiller Duval Body is characteristic of?

A

Yolk Sac Tumor

40
Q

What are the characteristics of Embryonal Carcinoma?

A

Malignant Tumor comprised of immature, primitive cells that produce glands

Forms hemorrhagic mess with negrosis

Could have elevated AFP or hCG

41
Q

What are the characteristics of Yolk sac tumor?

A

Resembles yolk sac elements

Most common in children

Schiller-Duval Bodies

AFP is elevated

42
Q

What are the characteristics of a Choriocarcinoma?

A

Malignant tumor of the syncytiotrophoblasts and cytotrophoblasts.

hCG is characteristially elevated leading to hyperthyroidism or gynecomastia

Reproduction and Sexuality (58 decks)

Brainscape helps you reach your goals faster, through stronger study habits.
© 2024 Bold Learning Solutions. Terms and Conditions