3.5.2 Treatment of Female Reproductive Disorders Flashcards

1
Q

What are the characteristics of premature puberty?

A

Puberty or thelarche before the age of 7 (causasian) or 6 (African American)

After age 6 or 7 if: Rapid progression of puberty. CNS findings or progression impacting emotional health of girl or family

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2
Q

What are some genetic mutations that could cause premature ovarian failure?

A
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3
Q

What are the characteristics of Hypergonadotropic Amenorrhea?

A

Elevated FSH

Premature ovarian failure

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4
Q

Fill in this chart

A
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5
Q

Is precocious puberty more common in girls or boys?

A

Girls

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6
Q

How can hormonal therapy be used to treat sexual dysfunction?

A
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7
Q

How would you treat a patient with central precocious puberty?

A

Use of depot GnRH agonist will result in regression or cessation of pubertal development

Early initiation will preserve growth

Many recommend cessation of treatment around age 11

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8
Q

What is important about androgen therapy for HSDD?

A
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9
Q

Describe the increase in sexual inactivity with age

A
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10
Q

What Tanner stage corresponds with the onset of menses?

A

Tanner stage 3

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11
Q

What are some treatment options for sexual pain disorders?

A

Pelvic floor physical therapy

Botox to overdevelop pelvic floor muscles

Dilator therapy

Lube

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12
Q

What is primary amenorrhea?

A

No menses with or without the appearance of other features of puberty

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13
Q

What is progressing precocoious puberty?

A

Progression between tanner stages w/in 3-6 months

Accelerated growth velocity

Advanced bone age

Falling off growth curve

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14
Q

What are some possible etiologies of Sexual arounsal disorder?

A

Menopause, surg, diaabeeeetus, neurologic disease, psychological, vascular

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15
Q

What is hypogonadotropic?

A

Hypothalamic (or pituitary) amenorrhea

Can be related to Anorexia, stress or exercise

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16
Q

What are some possible CNS findings in a patient with a pubertal disorder?

A
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17
Q

Fill in this chart

A
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18
Q

What is Sexual Arousal Disorder (FSAD)?

A

Persistent or recurring inability to attain or maintain sufficient sexual excitement - decreased lubrication or labial sensation

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19
Q

What is female sexual dysfunction?

A

The various ways in which an individual is unable to participate in a sexual relationship as she would wish

20
Q

What are some of the possible etiology of sexual pain disorders?

A
21
Q

How would you go about treating a patient with Sexual arousal disorder?

A

Sometimes a sex therapist needs to be consulted

22
Q

In an evaluation for a patient with a pubertal disorder what are some things you are looking at?

A
23
Q

What are the characteristics of puberty?

A

Puberty is the development of secondary sexual characteristics and menstruation in girls

Puberty requires the reactivation of the HPO axis and adrenal axis

Age of puberty has declined related to weight and nutrition

24
Q

Early age of adrenarche may be a sign of?

A

PCOS

25
Q

Describe the variability of the Menstrual cycle in adolescent females.

A
26
Q

Primary amenorrhea with significant adrenarche?

A

PCOS

27
Q

What occurs to initiate puberty?

A

GnRH regulates FSH and LH release - Pulsatility increases prior to puberty. Initially GnRH pulses occur during sleep

FSH is first to appear

LH pulsatility begins to mirror GnRH - maturation allows for the positive feedback by E2. Allowing the LH surge necessary for ovulation

28
Q

What is the average age of breast, pubic hair and menarche in puberty for US women?

A
29
Q

What is the prevalance of female sexual dysfunction?

A

43% of women

30
Q

What are some possibilities of problems that could cause peripheral precocious puberty?

A
31
Q

Describe androgen insufficiency in women

A
32
Q

What are some of the characteristics of the people and how they were affected according to the National Health and Social Life Survey?

A
33
Q

Describe the stages of reproductive aging?

A
34
Q

Describe the prevalence of Male and Female sexual complaints?

A
35
Q

Describe normal pubertal development in adolescent girls.

A
36
Q

What is hypoactive sexual desire disorder?

A

Persistent or recurring deficiency of sexual fantasies/thoughts and/ or receptivity to sexual activity

Etiology - Menopause, aging, endocrine abnormality or Medications

37
Q

What is a good benefit for pelvic pain disorder?

A

Physical therapy

38
Q

How does testosterone relate to female sexual function?

A

Data from younger oophorectomized women support role of testosterone in sexual desire and orgasm.

39
Q

What are some sexual pain disorders?

A

Dyspareunia - recurrent or persistent genital pain associated with sexual intercourse

Vaginismus - Recurrent or persistent involuntary spasms of the musculature of the outer third of the vagina that interferes with vaginal penetration

40
Q

What are the characteristics of primary amenorrhea?

A

Absence of menses by:

Age of 13 in the ansence of any secondary sexual characterisitics

Age 16 otherwise

41
Q

What are the 4 general categories of Female Sexual Dysfunction?

A

Libido

Arousal

Orgasm

Sexual Pain

42
Q

What are the WHO classifications of Amenorrhea?

A
43
Q

What groups of people are at risk for androgen deprivation?

A

Premature ovarian failure

Oophorectomy

Hypopituitarism

Addisons

Corticosteroid

Oral estrogen therapy

44
Q

What determines the age of menopause?

A

It is related to follicle deposition in ovary which is detemined prenatally

45
Q

What is androgen deprivation and what is important about it?

A

Androgen levels start to decline before age 30. At menopause - levels are half of that of a 30-40 year old. Abrupt change in androgen levels is not common with natural menopause but can be a prolen with surgical menopause