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#‼️ FITZPATRICK'S DERMATOLOGY 9TH EDITION (SHAMMY) > 29 - 200 - RADIOTHERAPY > Flashcards

29 - 200 - RADIOTHERAPY Flashcards

1
Q

Radiation-induced malignancy is a rare but serious side effect, which presents at a median of how many years after treatment?

A

10 years

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2
Q

refers to the delivery of specified radiation dose in temporally separate treatments, and is recommended to both increase the efficacy of effects on target tissue and to allow normal irradiated tissue to repair radiation damage

A

Fractionation

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3
Q

unit of radiation dose

A

gray (Gy)

*defined as 1 joule (J) of energy absorbed per kilogram of tissue

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4
Q

An alternate unit of absorbed dose, largely replaced by the gray

A

rad (an acronym for radiation absorbed dose)

*1 Gy is equal to 100 rads

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5
Q

Commonly used dose-fractionation schedules for cutaneous malignancies

A

60 Gy in 30 fractions, and 48 Gy in 12 fractions

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6
Q

The earliest reaction of radiation dermatitis

A

erythema

*may occur and resolve within hours, and is normally only evident after relatively high-dose exposure.

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7
Q

threshold dose for erythema in radiation dermatitis

A

2 Gy or greater skin dose

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8
Q

Classify the grade of radiation Dermatitis

Faint erythema

A

Grade 1

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9
Q

Classify the grade of radiation Dermatitis:

Patchy moist desquamation (mostly confined to skin folds and creases)

A

Grade 2

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10
Q

Classify the grade of radiation Dermatitis:

Dry Desquamation

A

Grade 1

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11
Q

Classify the grade of radiation Dermatitis:

Alopecia visible on close inspection

A

Grade 1

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12
Q

Classify the grade of radiation Dermatitis:

**Atrophy associated with telangiectasia or pigmentation changes **

A

Grade 1

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13
Q

Classify the grade of radiation Dermatitis:

Mild induration or fibrosisl able to pinch skin

A

Grade 1

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14
Q

Classify the grade of radiation Dermatitis:

Moderate-to-brisk erythema

A

Grade 2

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15
Q

Classify the grade of radiation dermatitis:

Moderate edema

A

Grade 2

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16
Q

Classify the grade of radiation dermatitis:

Hair loss ≥50% of normal

A

Grade 2

17
Q

Classify the grade of radiation Dermatitis:

Striae or adnexal structure loss

A

Grade 2

18
Q

Classify the grade of radiation dermatitis:

Moderate induration or fibrosis; able to SLIDE skin but unable to pinch

A

Grade 2

19
Q

Classify the grade of radiation dermatitis:

**Bleeding induced by minor trauma or abrasion **

A

Grade 3

20
Q

Classify the grade of radiation dermatitis:

**Moist desquamation (other than skin folds and creases) **

A

Grade 3

21
Q

Classify the grade of radiation dermatitis:

Atrophy = Ulceration

A

Grade 3

22
Q

Classify the grade of radiation dermatitis:

**Severe induration or fibrosis; ** unable to slide or pinch, limiting self care

A

Grade 3

23
Q

Classify the grade of radiation dermatitis:

**Skin Necrosis **

A

Grade 4

24
Q

Classify the grade of radiation dermatitis:

Ulceration of full thickness of dermis

A

Grade 4

25
Q

Classify the grade of radiation dermatitis:

**Spontaneous bleeding **

A

Grade 4

26
Q

Classify the grade of radiation dermatitis:

Generalized induration or fibrosis; impaired breathing or feeding

A

Grade 4

27
Q

Classify the grade of radiation dermatitis:

Death

A

Grade 5

28
Q

cutaneous reaction, in response to specific systemic agents, in the area of previous radiation exposure.

A

Radiation recall

29
Q

The most commonly cited chemotherapeutic agents in radiation racall are?

A

anthracyclines, taxanes, and gemcitabine

30
Q

Cutaneous Indications for Primary or Adjuvant Radiotherapy

A
31
Q

The clearest indication for adjuvant radiotherapy treatment

A

positive surgical margin

other considerations include tumor depth greater than 4 mm in the case of squamous cell cancer or tumor size greater than 2 cm

32
Q

Commonly-Observed Adverse Events Attributable to Radiation

A

#‼️ FITZPATRICK'S DERMATOLOGY 9TH EDITION (SHAMMY) (128 decks)

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