25 - 166 - POXVIRUS Flashcards
Which of the following statements on smallpox is FALSE?
a. Involvement of all parts of the body, excluding the palms and soles, occurs within 24 to 48 hours
b. A key characteristic is that all lesions progress synchronously through all stages.
c. After their resolution, pitted scars remain on 65% to 80% of survivors
d. Individuals with Flat Smallpox become severely ill with toxic fever and most die with hemorrhagic lesions
A
Which of the following can definitively confirm the presence of Monkeypox infection?
a. Presence of Guarneri bodies on histopathology
b. PCR analysis of a swab or crust
c. Electron microscopy findings
d. All of the above
B
Which is an indication for vaccination for Monkeypox?
a. Postexposure vaccination for those within 4 days of direct exposure to monkeypox virus; should be considered up to 14 days after exposure.
b. Postexposure vaccination for those within 7 days of direct exposure to monkeypox virus; should be considered up to 14 days after exposure.
c. Postexposure vaccination for those within 10 days of direct exposure to monkeypox virus; should be considered up to 14 days after exposure.
d. Postexposure vaccination for those within 14 days of direct exposure to monkeypox virus; should be considered up to 14 days after exposure.
A
How is the Monkeypox virus transmitted in humans?
a. Fomites
b. Contact with infected bodily fluids
c. Aerosolization of the virus
d. B and C
e. All of the above
E
Lymphadenopathies in Monkeypox patients are seen in these areas EXCEPT?
a. Inguinal
b. Cervical
c. Submandibular
d. Supraclavicular
e. All of the above are affected
D
Which of the following is NOT a known complication of Monkeypox infection?
a. Secondary bacterial infection
b. Encephalitis
c. Corneal Scarring
d. Arthralgia and Myalgia
e. All of the above are known complications
D
Which of the following is FALSE regarding Orf infection?
a. The virus can be found in reindeers and gazelles
b. Orf lesions evolve through 6 clinical stages
c. The regenerative stage of Orf are composed of dried out lesions and black dots composed of pyknotic cells on the surface
d. According to the CDC, human to human transmission of the infection has been documented
D
Where can molluscum contagiosum lesions occur in humans?
a. skin
b. eyes
c. genitals
d. A and B only
e. All of the above
E
Molluscum contagiosum is associated with a CD4+ count of?
a. <200 cells/ul
b. <300 cells/ul
c. <400 cells/ul
d. No definitive association has been established
A
Which of the following is the preferred treatment of molluscum contagiosum in children?
a. imiquimod
b. cantharidin
c. potassium hydroxide
d. topical tretinoin
B
what molluscum genotype is primarily seen in adults and immunocompromised?
genotype 2
*most commonly transmitted by sexual contact
incubation period of molluscum
2 - 6 weeks
viral inclusion bodies of molluscum
Henderson-Paterson Bodies
molluscum infection is associated with a CD4+ count of how many?
< 200 cells/uL
most commonly used therapy for molluscum
Cantharidin
Cantharidin 0.7% in a collodion base is applied to the lesions and washed off after 2 to 6 hours.
