16 - 86 - TELOGEN EFFLUVIUM Flashcards

1
Q

characterized by increased telogen club hair shedding

A

Telogen effluvium

TE is best characterized by a premature termination of the anagen (growing) phase of hair follicles, with a resultant increase in telogen (resting) phase hairs leading to excessive and diffuse loss of club hairs

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2
Q

most common cause of diffuse hair loss

A

Telogen effluvium

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2
Q

triggers of telogen effluvium

A

febrile diseases, childbirth, emotional disturbance, chronic systemic diseases, or the administration of heparin

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3
Q

the loss of more than how many percent of scalp hairs has been reported to be necessary to clinically detect diffuse hair loss?

A

more than 25%

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4
Q

Irrespective of clinical subtypes, what the most representative manifestation of TE?

A

diffuse excessive shedding of club hairs

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5
Q

in acute TE, acute and diffuse hair shedding is noted how many months from causative events?

A

2 to 4 months

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6
Q

Usually gradual decrease and termination of hair shedding and the regrowth of new anagen hairs in acute TE can be expected by how many months?

A

3 to 6 months.

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7
Q

chronic diffuse telogen hair loss occurs more than how many months?

A

more than 6 months

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8
Q

give exemples of causes of acute TE

A
  • Effluvium of the newborn
  • Febrile illness
  • Surgery
  • Pregnancy
  • Weight loss (crash diet)
  • Drugs (may cause CDTHL)
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9
Q

causes of Chronic diffuse telogen hair loss (CDTHL)

A
  • Thyroid disease
  • Aging Malnutrition
  • Iron deficiency (controversial)
  • Zinc deficiency (severe cases)
  • Systemic illness
  • Psychological stress (controversial)
  • STD (HIV infection and syphilis)

The relation between CDTHL and the causative factors needs to be reversible and reproducible.

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9
Q

cause of Chronic telogen effluvium

A

Idiopathic (shortening of anagen)

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10
Q

On average, telogen hair accounts for around how many % of scalp hairs?

A

10% (Normal)

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11
Q

in effluvium of the Newborn, the shedding starts within how many months after birth?

A

4 months

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12
Q

This type of effluvium may be regarded as “total replacement of the first pelage completed before the first 6 month of life.

A

effluvium of the Newborn

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13
Q

after a febrile illness, hair shedding appears how many months after the illness and continued for how many weeks?

A

Hair shedding appeared 3 to 4 months after the illness and continued for 3 to 4 weeks

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14
Q

Postpartum alopecia or telogen gravidarum is probably the most widely recognized form of classic TE observed how many months after childbirth?

A

2 to 3 months

15
Q

thyroid disease associated with TE

Hair regrowth can be observed around how many weeks after the initiation of thyroid hormone replacement?

A

hypothyroidism

8 weeks

16
Q

A vigorous weight loss (11.7 to 24.75 kg within 3 weeks to 3 months) can result in remarkable increase in telogen counts (25% to 50%) and lead to acute TE.

Calorie restriction of how many kcal per day has been reported to be associated with hair loss?

17
Q

represents a main mechanism of drug-induced TE

A

Early entry of anagen hair follicles into telogen

18
Q

In many cases of drug-induced TE, the shedding starts how manymonths after the initiation of the medication?

A

2 - 3 months

Usually, the recovery from TE can be expected around 3 months after the termination of a causative drug

19
Q

Identify the mechanism/ pathophysiology of TE involved

20
Q

Identify the mechanism/ pathophysiology of TE involved

anagen period is prolonged in most hair follicles but eventually terminated, resulting in an abrupt increase in telogen hairs

A

DELAYED ANAGEN RELEASE

20
Q

Identify the mechanism/ pathophysiology of TE involved

febrile illness

A

IMMEDIATE ANAGEN RELEASE

20
Q

Identify the mechanism/ pathophysiology of TE involved

drug- or stress-induced TE respectively represented by those induced by heparin and drugs in the heparin family

A

IMMEDIATE ANAGEN RELEASE

Premature termination of anagen and entry into telogen

21
# Identify the mechanism/ pathophysiology of TE involved postpartum period
DELAYED ANAGEN RELEASE
21
# Identify the mechanism/ pathophysiology of TE involved TE may result from earlier entry into anagen as the frequency of hair shedding should increase
IMMEDIATE TELOGEN RELEASE
22
# Identify the mechanism/ pathophysiology of TE involved etretinate-treated patients
SHORT ANAGEN ## Footnote * idiopathic anagen shortening could be observed in some individuals * shorter anagen results in a higher telogen rate, with resultant effluvium
23
# Identify the mechanism/ pathophysiology of TE involved initiation of topical minoxidil
IMMEDIATE TELOGEN RELEASE
24
# Identify the mechanism/ pathophysiology of TE involved The telogen phase is sustained in this case but immediately after, the anagen is initiated, resulting in an increase in shedding club hairs
DELAYED TELOGEN RELEASE
25
# Identify the mechanism/ pathophysiology of TE involved **seasonal molting** in mammals and, probably, in humans traveling from **low-daylight to high daylight conditions**
DELAYED TELOGEN RELEASE
26
# Identify the mechanism/ pathophysiology of TE involved term during which club hairs are shed from the telogen root sheath sac
Exogen