26 - 172 - CHANCROID

Question 1

sexually transmitted acute ulcerative disease usually localized at the anogenital area and often associated with inguinal adenitis or bubo

Answer 1

Chancroid

Question 2

causative agent of chancroid

Answer 2

Haemophilus ducreyi—a Gram-negative, facultative anaerobic coccobacillus

Question 3

characterize the ulcer of chancroid

Answer 3

**Painful, soft ulcers with ragged undermined margins **develop 1 to 2 weeks after inoculation (usually prepuce and frenulum in men and vulva, cervix, and perianal areas in women)

Question 4

The duration of infectivity of chancroid in the absence of treatment

Answer 4

45 days for women

Question 5

incubation period of chancroid

Answer 5

3 and 7 days, rarely more than 10 days

Question 5

areas of predilection of chancroid in males

Answer 5

external or internal surface of the prepuce, frenulum, glans

Question 6

areas of predilection of chancroid in females

Answer 6

vulva, fourchette, labia minora, vestibule

Question 7

The 3 classic etiologic agents for genital ulceration

Answer 7

(a) H. ducreyi, (b) Treponema pallidum, and (c) herpes simplex

Question 8

Question 8

identify the clinical variant

Single lesion extends peripherally and shows extensive ulceration.

Answer 8

Giant chancroid

Question 9

identify the clinical variant

Lesion that becomes confluent, spreading by extension and autoinoculation.
The groin or thigh may be involved (Ulcus molle serpiginosum).

Answer 9

Large serpiginous ulcer

Question 10

identify the clinical variant

Variant caused by superinfection with fusospirochetes.
Rapid and profound destruction of tissue can occur (Ulcus molle gangrenosum).

Answer 10

Phagedenic chancroid

Question 11

identify the clinical variant

Small ulcer that resolves spontaneously in a few days may be followed 2 to 3 weeks later by acute regional lymphadenitis (French: chancre mou volant).

Answer 11

Transient chancroid

Question 12

identify the clinical variant

Multiple small ulcers in a follicular distribution

Answer 12

Follicular chancroid

Question 13

identify the clinical variant

Granulomatous ulcerated papule may resemble donovanosis or condylomata lata (Ulcus molle elevatum)

Answer 13

Papular chancroid

Question 14

most frequent complaint of chancroid

Answer 14

local pain

Question 15

treatment regimen for chancroid

Answer 15

Question 16

what is the preferred drug if patient with chancroid is pregnant

Answer 16

ceftriaxone