22 - 149 - WOUND HEALING Flashcards
Essential step for wound resurfacing
A. Coagulation
B. Keratinocyte migration
C. Fibroblast migration
D. Collagen formation
B
Medical therapy that accelerates healing of venous ulcer
A. Stanozolol
B. Danazol
C. Glucocorticoid
D. Pentoxyfylline
D
Acellular skin substitute approved for burns and diabetic foot ulcer
A. Integra
B. Porcine small intestine submucosa
C. Cadaveric allograft
D. Dehydrated human amnion
A
Major stimulus for V
A. Ki67
B. Hypoxia
C. PDGF
D. Contraction
B
Only growth factor approved by US FDA for wound healing
A. PDGF-BB
B. FGF-10
C. TGF-B1
D. VEGF-A
A
closure of the wound soon after wound creation, as seen in surgical wounds and clean lacerations
Primary healing
slightly delayed closure of a wound, typically by a few days
Delayed primary healing
the open wound heals through a process that includes granulation tissue formation and epithelialization.
Commonly employed after an excessive loss of soft tissue, such as major trauma or severe burns, the large defect requires ingrowth of granulation tissue and extracellular matrix (ECM) formation
secondary intention
These cells play a major role in secondary intention healing
Myofibroblasts
appearing 3 days after the injury and reaching a maximum level 10 to 21 days postinjury.
This type of healing may result in wound contracture and can cause functional restriction
Secondary intention healing
occurs when a wound originally closed by primary intention dehisces and then heals by secondary intention
Tertiary intention
Phases of wound healing