17 - 92 - POLYMORPHIC LIGHT ERUPTION Flashcards
most common photodermatosis, with a high prevalence, particularly among young women, in temperate climates
Polymorphic light eruption (PMLE)
areas spared in Polymorphic light eruption (PMLE)
face and hands
- presumably because of continuous natural hardening resulting from daily sun exposure
most common form of Polymorphic light eruption (PMLE)
The papular form, characterized by large or small separate or confluent erythematous and edematous papules that may form clusters, is most common
Diagnostic Criteria for Polymorphic Light Eruption
When is photoprovocation best perfomed
Photoprovocation is best performed before the beginning of the sunny summer season, preferentially in early spring, to avoid the false-negative results that may occur when the test is done too late in the season (ie, late spring or summer) because of tolerance induction through natural photohardening.
principles of photoprovocation
- 2 symmetrically located test areas at predilection sites, preferably on previously involved skin, are exposed daily for 4 to 5 days to increasing suberythemal or near-erythemal doses of UVA or UVB radiation (or solar-simulated UV radiation).
suggested pathophysiology of PMLE
resistance to ultraviolet (UV)-induced immune suppression with subsequent delayed-type hypersensitivity reaction against UV-induced antigen(s)
T or F. Sunburn is not mandatory for the development of a PMLE skin rash.
True
Most common primary lesion of PMLE
Papule