17 - 94 - HYDROA VACCINIFORME

Question 1

Hydroa Vacciniforme is sometimes associated with what virus?

Answer 1

Epstein-Barr virus infection

Question 2

only established therapy for hydroa vacciniforme

Answer 2

Avoidance of ultraviolet radiation including the use of broad-spectrum sunscreens

Question 3

rare, chronic photodermatosis with onset typically occurring in childhood and a tendency to remission in adolescence

characterized by photoinduced papules and vesicles that invariably scar after healing

Answer 3

Hydroa vacciniforme (HV)

Question 4

Answer 4

Figure 94-1 Hydroa vacciniforme. Vesicular, bullous, and crusted facial lesions, which heal with vacciniform scars.

HV eruptions typically occur in summer, 3 often with an intense burning or stinging sensation followed by the appearance of individual or confluent papules and then vesicles, all within hours of sunlight exposure (Fig. 94-1). This is followed by umbilication, crusting, and progression to permanent pock scarring within weeks.

Question 5

Question 6

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Question 8

Which of the following is false regarding Hydroa Vacciniforme?

A. The disease has its onset in puberty

B. Patients with dark pigmentation are affected preferentially

C. There is female predominance for severe forms

D. Cases of HV are normally sporadic

Answer 8

C

Question 9

Which of the following is not included regarding the primary and secondary lesions of Hydroa Vacciniforme?

A. Vesicles

B. Nodules

C. Umbilication

D. Crusting

E. Pock scars

Answer 9

B

Question 10

True or false: Its clear relationship to sunlight exposure, its distribution, and its early clinical appearances are all similar to that of polymorphous light eruption (PMLE).

Answer 10

True

Question 11

Choose the correct statement.

A. EBV nucleic acids are found in the cutaneous lesions of HV in 85% to 95% of patients, but not in lesional skin of control patients

B. HHV-6 nucleic acids are found in the cutaneous lesions of HV in 85% to 95% of patients, but not in lesional skin of control patients

C. EBV nucleic acids are found in the cutaneous lesions of HV in 85% to 95% of patients and in lesional skin of control patients

D. HHV-6 nucleic acids are found in the cutaneous lesions of HV in 85% to 95% of patients, and in lesional skin of control patients

Answer 11

A

Question 12

Which of the following is not true regarding Hydroa Vacciniforme?

A. HV often resolves in adolescence

B. It often proves to be a refractory disease

C. Prophylactic phototherapy with narrowband ultraviolet B or psoralen and ultraviolet A, particularly psoralen and ultraviolet A is ineffective

D. In mild cases of HV, sun avoidance and sunscreen use prevent HV eruptions

Answer 12

C