1.1.4 Raine Et Al Study (Bi) Flashcards

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1
Q

What is Research Hypothesis 1?

A

Dysfunction in brain structures such as the prefrontal cortex, corpus callosum, left angular gyrus and limbic system will be found more often in murderers than a control group of non murderers

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2
Q

What is the purpose of the control group?

A

Baseline for comparison

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3
Q

Is Research hypothesis 1 adirectional, non directional or a null hypothesis?

A

Directional

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4
Q

What is research hypothesis 2?

A

Dysfunction in brain structures such as the prefrontal cortex, corpus callosum, left angular gyrus and limbic system will be found more often in murderers, than dysfunction in other areas of the brain that have been implicated in non violent psychiatric disorders

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5
Q

Is research hypothesis 2 directional, non directional or null?

A

Directional

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6
Q

Where is the left angular gyrus found?

A

In the parietal lobe

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7
Q

What components make up the limbic system?

A

Amygdala Hippocampus Thalamus

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8
Q

Methodology

A
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9
Q

What was Raine et al’s research method and what does this mean?

A

Raine et al used a quasi-experiment, this means the IV is naturally occurring

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10
Q

What was the IV in Raines experiment?

A

Not guilty by reason of insanity (NGRI) or not

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11
Q

What was the DV in Raines experiment?

A

Dysfunction in different brain areas

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12
Q

How was the DV operationalised?

A

Using PET scan results to see metabolic activity in the brain

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13
Q

Who were the subjects (participants) in Raines study?

A

A group of 41 prisoners all charged with murder but who pleaded not guilty by reason of insanity

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14
Q

Reasons for the 41 offendeds to prove their diminished capacity were

A

Their specific mental disorder

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15
Q

What does NGRI mean?

A

Not guilty by reason of insanity

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16
Q

Where were the participants charged with murder or manslaughter?

A

In California

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17
Q

How many offenders gave schizophrenia as a reason

A

6

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18
Q

How many offenders gave history of head injury/brain damage as a reason

A

23

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19
Q

How many offenders gave history of drug abuse as a reason

A

3

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20
Q

How many offenders gave affective disorder as a reason

A

2

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21
Q

How many offenders gave epilepsy as a reason

A

2

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22
Q

How many offenders gave history of learning disability as a reason

A

3

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23
Q

How many offenders gave personality disorder as a reason

A

2

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24
Q

What gender were the participants?

A

39 were male 2 were female

25
Q

What was the average age of the participants?

A

34.3 years

26
Q

What happened the two weeks before brain scanning?

A

No murderer was given psychoactive medication

27
Q

How many patients were referred for scanning due to schizophrenia?

A

• 6

28
Q

How many subjects were referred for scanning due to brain damage/ head injury?

A

23

29
Q

What was each subject matched with?

A

A non murderer subject

30
Q

How were the subjects and controlled matched?

A

As closely as possible for: • age • gender • schizophrenia

31
Q

What did all controls undergo?

A

Screening for mental illness, drug taking and history of murder

32
Q

What group did the non murderers make up?

A

The control group

33
Q

Procedures

A
34
Q

How were the pps selected

A

Oportunity sampling

35
Q

Give a brief outline of the procedure raine used:

A

• injection • continuous performance task • PET scan

36
Q

What were all participants injected with?

A

A tracer substance that was taken up by the brain to show the location of brain metabolism (fluorodeoxyglucose/FDG)

37
Q

How long did it take for the FDG to be taken up by the brain

A

32 minuets

38
Q

What was the CPT the participants underwent and when was it done?

A
  • Detecting signals, designed to activate target areas of the brain
  • Done straight after the drug was administered
39
Q

When was the PET scan given?

A

After the 32 minuets

40
Q

What does a PET scan involve

A

10 horizontal slices of the brain were recorded using the corticle peel and box techniques

41
Q

What was the PET scan used to show activity in?

A

6 main areas outside the brain (cortical) 8 main area inside the brain (subcortical)

42
Q

What did raine et al’s study focus on?

A

Brain scans of violent individuals who has committed murder and pleaded not guilty by reason of insanity

43
Q

What did Raines procedure do to get its sample

A

Opportunity sampling - Raine selected his subjects from those referred for scanning

44
Q

What did Raines findings show for the prefrontal cortex?

A

Lower metabolic activity in murderers than in controls Lower activity is linked to loss of self control and altered emotion

45
Q

What did Raines findings show for the parietal cortex?

A

Murderers showed lower activity levels especially in the left angular gyrus Lower activity is linked to low verbal ability, leading to education failure and thus crime

46
Q

What did Raines findings show about the temporal cortex?

A

No difference

47
Q

What did Raines findings show about the corpus callosum?

A

Lower activity in murderers Lower activity was expected as it could stop the left hemisphere inhibiting the rights violence

48
Q

What did Raines findings show about the amygdala?

A

Lower activity in the left in murderers

49
Q

What did Raines findings show about the thalamus?

A

Higher activity in the right side

50
Q

What did Raines findings show about the medial temporal?

A

Lower activity in the left compared to the right in murderers

51
Q

Found reduced activity (lower glucose metabolism) in the brain of NGRI pps in areas previously linked to violence

A
  • Prefrontal cortex
  • Parietal lobe
  • Corpus Callosum
  • Left hemisphere - amygdala, thalamus, and hippocampus
52
Q

Found increased activity (higher glucose metabolism) in the brain of NGRI pps in areas not previously linked to violence

A
  • Cerebellum
  • Occipital lobe
  • Right hemisphere - amygdala, thalamus and hippocampus
53
Q

What conclusions did Raines draw about the amygdala, medial temporal and thalamus?

A

These structures all for the limbic system (emotion) Problems may result in inhibition for violent behaviour, fearlessness and failure to learn the negative effects of violence

54
Q

What did the cinguate, caudate, putamen, globus pallidus and cerebellum show?

A

No difference

55
Q

Conclusions - Raines research showed differences in what?

A

The brains of murderers pleading NGRI

56
Q

Conclusions - Raines research does not suggest violence is what?

A

Biologically determined

57
Q

Raines research does not excuse what?

A

The behaviour of NGRI murderers

58
Q
A