Topical Antifungal and Antiviral Agents Flashcards
There is only 1 topical Antiviral agent. What is it?
Acyclovir
There is only 1 topical Antiviral agent. What is it?
Acyclovir
What is Acyclovir?
Topical Antiviral agent
What does Acyclovir treat?
Orolabial herpes simplex virus infection
What does Acyclovir treat?
Orolabial herpes simplex virus infection
The rest of the cards in this deck (besides Acyclovir) will be what type of topical agents?
AntiFUNGAL
MOA for the group of Imidazoles?
Block ergosterol synthesis
What 4 topical Antifungal agents are Imidazoles?
Miconazle
Clotrimazole
Efinaconazle
Ketoconazle
What 4 topical Antifungal agents are Imidazoles?
Miconazle
Clotrimazole
Efinaconazle
Ketoconazle
Group and MOA for Miconazle, Clotrimazole, Efinaconazle, Ketoconazle?
Topical Antifungal agents = Imidazoles
MOA = block ergosterol synthesis
Adverse side effects that may be seen with the Imidazole group?
(Miconazle, Clotrimazole, Efinaconazle, Ketoconazle)
= Stinging, itching, redness, local irritation
What does Miconazle treat?
Vulvovaginal candidiasis
What 2 things can Clotrimazole treat?
Athletes foot
Vulvovaginal candidiasis
What does Efinaconazle treat?
Onychomycosis - given for 48 weeks
What 3 things can Ketoconazle treat?
Dermatophytes
Candidiasis
Seborrheic dermatitis
There are 5 topical Antifungal agents that are NOT part of the Imidazole group. Name them.
Ciclopirox Terbinafine Tolnaftate Nystatin Amphotericin B
There are 5 topical Antifungal agents that are NOT part of the Imidazole group. Name them.
Ciclopirox Terbinafine Tolnaftate Nystatin Amphotericin B
MOA for Ciclopirox
Disrupts macromolecular synthesis
What does Ciclopirox treat? (3)
Dermatophytes, candida, malessezia
MOA for Terbinafine
Inhibits squalene epoxidase
What does Terbinafine treat? (1)
Dermatophytes
MOA for Tolnaftate
UNKNOWN
What does Tolnaftate treat? (2)
Dermatophytes and malessezia
MOA for Nystatin
Alters membrane permeability
What does Nystatin treat? (1)
Mucosal and cutaneous candida infections
When using Nystatin to treat mucosal candida infections, what should the patient do?
Hold Nystatin in their mouth and do NOT swallow
MOA for Amphotericin B
Alters membrane permeability
What does Amphotericin B treat? (1)
Cutaneous candida infections
If Amphotericin B is given via IV, what are there possible adverse effects?
Fever, cramps, nausea/vomit, changes in urination and arrhythmias
What topical Antifungal agents can treat cutaneous candida infections?
Nystatin
Amphotericin B
What topical Antifungal agents can treat dermatophytes?
Ciclopirox
Terbinafine
Tolnaftate
What topical Antifungal agents can treat malessezia?
Ciclopirox
Tolnaftate
