Topical Antifungal and Antiviral Agents

Question 1

There is only 1 topical Antiviral agent. What is it?

Answer 1

Acyclovir

Question 2

There is only 1 topical Antiviral agent. What is it?

Answer 2

Acyclovir

Question 3

What is Acyclovir?

Answer 3

Topical Antiviral agent

Question 4

What does Acyclovir treat?

Answer 4

Orolabial herpes simplex virus infection

Question 5

What does Acyclovir treat?

Answer 5

Orolabial herpes simplex virus infection

Question 6

The rest of the cards in this deck (besides Acyclovir) will be what type of topical agents?

Answer 6

AntiFUNGAL

Question 7

MOA for the group of Imidazoles?

Answer 7

Block ergosterol synthesis

Question 8

What 4 topical Antifungal agents are Imidazoles?

Answer 8

Miconazle
Clotrimazole
Efinaconazle
Ketoconazle

Question 9

What 4 topical Antifungal agents are Imidazoles?

Answer 9

Miconazle
Clotrimazole
Efinaconazle
Ketoconazle

Question 10

Group and MOA for Miconazle, Clotrimazole, Efinaconazle, Ketoconazle?

Answer 10

Topical Antifungal agents = Imidazoles

MOA = block ergosterol synthesis

Question 11

Adverse side effects that may be seen with the Imidazole group?

Answer 11

(Miconazle, Clotrimazole, Efinaconazle, Ketoconazle)

= Stinging, itching, redness, local irritation

Question 12

What does Miconazle treat?

Answer 12

Vulvovaginal candidiasis

Question 13

What 2 things can Clotrimazole treat?

Answer 13

Athletes foot

Vulvovaginal candidiasis

Question 14

What does Efinaconazle treat?

Answer 14

Onychomycosis - given for 48 weeks

Question 15

What 3 things can Ketoconazle treat?

Answer 15

Dermatophytes
Candidiasis
Seborrheic dermatitis

Question 16

There are 5 topical Antifungal agents that are NOT part of the Imidazole group. Name them.

Answer 16

Ciclopirox
Terbinafine
Tolnaftate
Nystatin
Amphotericin B

Question 17

There are 5 topical Antifungal agents that are NOT part of the Imidazole group. Name them.

Answer 17

Ciclopirox
Terbinafine
Tolnaftate
Nystatin
Amphotericin B

Question 18

MOA for Ciclopirox

Answer 18

Disrupts macromolecular synthesis

Question 19

What does Ciclopirox treat? (3)

Answer 19

Dermatophytes, candida, malessezia

Question 20

MOA for Terbinafine

Answer 20

Inhibits squalene epoxidase

Question 21

What does Terbinafine treat? (1)

Answer 21

Dermatophytes

Question 22

MOA for Tolnaftate

Answer 22

UNKNOWN

Question 23

What does Tolnaftate treat? (2)

Answer 23

Dermatophytes and malessezia

Question 24

MOA for Nystatin

Answer 24

Alters membrane permeability

Question 25

What does Nystatin treat? (1)

Answer 25

Mucosal and cutaneous candida infections

Question 26

When using Nystatin to treat mucosal candida infections, what should the patient do?

Answer 26

Hold Nystatin in their mouth and do NOT swallow

Question 27

MOA for Amphotericin B

Answer 27

Alters membrane permeability

Question 28

What does Amphotericin B treat? (1)

Answer 28

Cutaneous candida infections

Question 29

If Amphotericin B is given via IV, what are there possible adverse effects?

Answer 29

Fever, cramps, nausea/vomit, changes in urination and arrhythmias

Question 30

What topical Antifungal agents can treat cutaneous candida infections?

Answer 30

Nystatin | Amphotericin B

Question 31

What topical Antifungal agents can treat dermatophytes?

Answer 31

Ciclopirox Terbinafine Tolnaftate

Question 32

What topical Antifungal agents can treat malessezia?

Answer 32

Ciclopirox | Tolnaftate