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SBL > Topical Antifungal and Antiviral Agents > Flashcards

Topical Antifungal and Antiviral Agents Flashcards

1
Q

There is only 1 topical Antiviral agent. What is it?

A

Acyclovir

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2
Q

There is only 1 topical Antiviral agent. What is it?

A

Acyclovir

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3
Q

What is Acyclovir?

A

Topical Antiviral agent

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4
Q

What does Acyclovir treat?

A

Orolabial herpes simplex virus infection

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5
Q

What does Acyclovir treat?

A

Orolabial herpes simplex virus infection

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6
Q

The rest of the cards in this deck (besides Acyclovir) will be what type of topical agents?

A

AntiFUNGAL

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7
Q

MOA for the group of Imidazoles?

A

Block ergosterol synthesis

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8
Q

What 4 topical Antifungal agents are Imidazoles?

A

Miconazle
Clotrimazole
Efinaconazle
Ketoconazle

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9
Q

What 4 topical Antifungal agents are Imidazoles?

A

Miconazle
Clotrimazole
Efinaconazle
Ketoconazle

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10
Q

Group and MOA for Miconazle, Clotrimazole, Efinaconazle, Ketoconazle?

A

Topical Antifungal agents = Imidazoles

MOA = block ergosterol synthesis

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11
Q

Adverse side effects that may be seen with the Imidazole group?

A

(Miconazle, Clotrimazole, Efinaconazle, Ketoconazle)

= Stinging, itching, redness, local irritation

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12
Q

What does Miconazle treat?

A

Vulvovaginal candidiasis

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13
Q

What 2 things can Clotrimazole treat?

A

Athletes foot

Vulvovaginal candidiasis

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14
Q

What does Efinaconazle treat?

A

Onychomycosis - given for 48 weeks

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15
Q

What 3 things can Ketoconazle treat?

A

Dermatophytes
Candidiasis
Seborrheic dermatitis

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16
Q

There are 5 topical Antifungal agents that are NOT part of the Imidazole group. Name them.

A 
Ciclopirox
Terbinafine
Tolnaftate
Nystatin
Amphotericin B
17
Q

There are 5 topical Antifungal agents that are NOT part of the Imidazole group. Name them.

A 
Ciclopirox
Terbinafine
Tolnaftate
Nystatin
Amphotericin B
18
Q

MOA for Ciclopirox

A

Disrupts macromolecular synthesis

19
Q

What does Ciclopirox treat? (3)

A

Dermatophytes, candida, malessezia

20
Q

MOA for Terbinafine

A

Inhibits squalene epoxidase

21
Q

What does Terbinafine treat? (1)

A

Dermatophytes

22
Q

MOA for Tolnaftate

A

UNKNOWN

23
Q

What does Tolnaftate treat? (2)

A

Dermatophytes and malessezia

24
Q

MOA for Nystatin

A

Alters membrane permeability

25
Q

What does Nystatin treat? (1)

A

Mucosal and cutaneous candida infections

26
Q

When using Nystatin to treat mucosal candida infections, what should the patient do?

A

Hold Nystatin in their mouth and do NOT swallow

27
Q

MOA for Amphotericin B

A

Alters membrane permeability

28
Q

What does Amphotericin B treat? (1)

A

Cutaneous candida infections

29
Q

If Amphotericin B is given via IV, what are there possible adverse effects?

A

Fever, cramps, nausea/vomit, changes in urination and arrhythmias

30
Q

What topical Antifungal agents can treat cutaneous candida infections?

A

Nystatin

Amphotericin B

31
Q

What topical Antifungal agents can treat dermatophytes?

A

Ciclopirox
Terbinafine
Tolnaftate

32
Q

What topical Antifungal agents can treat malessezia?

A

Ciclopirox

Tolnaftate

SBL (48 decks)

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