AIDS - opportunistic infections Flashcards

1
Q

What is the most common opportunistic infection?

A

Pneumocystis Jirovecii Pneumonia (PJP)

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2
Q

Symptoms of infection with Pneumocystis Jirovecii Pneumonia?

A

Fever, non-productive cough, dyspnea, pleuritic chest pain

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3
Q

What is the most common physical exam finding with Pneumocystis Jirovecii Pneumonia?

A

Exertional Hypoxia

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4
Q

What does a CT scan show with Pneumocystis Jirovecii Pneumonia?

A

Ground-glass infiltrates in the lungs

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5
Q

Fever, dyspnea, non-productive cough, exertional hypoxia are seen with what opportunistic infection?

A

Pneumocystis Jirovecii Pneumonia

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6
Q

Ground-glass infiltrates in the lungs will be seen with what opportunistic infection?

A

Pneumocystis Jirovecii Pneumonia

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7
Q

PJP occurs with CD4 count less than?

A

200

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8
Q

How do you diagnose PJP?

A

Bronchoalveolar lavage

Sputum analysis

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9
Q

Mycobacterium Tuberculosis occurs with CD4 count less than?

A

500

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10
Q

Symptoms of infection with Mycobacterium Tuberculosis?

A

Fever, cough, dyspnea, weight loss, night sweats

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11
Q

Fever, cough, dyspnea, weight loss, night sweats

A

Mycobacterium Tuberculosis

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12
Q

What will be present in imaging of the lungs with Mycobacterium Tuberculosis?

A

Apical cavitary lesion in upper lung fields

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13
Q

Apical cavitary lesion in the upper lung fields will be seen with what opportunistic infection?

A

Mycobacterium Tuberculosis

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14
Q

What CD4 count is necessary to get Community Acquired Pneumonia?

A

ANY

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15
Q

Symptoms of Community Acquired Pneumonia?

A

Fever, cough, shortness of breath, chest infiltrates

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16
Q

2 typical organisms that cause Community Acquired Pneumonia?

A

Strep. Pneumoniae

H. Influenzae

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17
Q

CNS Toxoplasmosis occurs with a CD4 count less than?

A

100

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18
Q

What toxoplasma antibody will be (+) in toxoplasmosis?

19
Q

How do you get CNS toxoplasmosis?

A

Reactivation of latent tissue cysts in patients with prior toxoplasmosis infection

20
Q

Symptoms of CNS Toxoplasmosis?

A

Fever, headache and FOCAL NEURO DEFICITS

21
Q

Fever, headache and focal neuro deficits?

A

CNS Toxoplasmosis

22
Q

What will be seen on MRI with CNS toxoplasmosis infection?

A

MULTIPLE ring-enhancing lesions

23
Q

Primary CNS Lymphoma can present similar to?

A

CNS toxoplasmosis

24
Q

Primary CNS lymphoma occurs with a CD4 count less than?

25
Symptoms of Primary CNS lymphoma?
Fever, headache and FOCAL NEURO DEFICITS
26
Primary CNS lymphoma and CNS Toxoplasmosis have the same symptoms. What does Primary CNS lymphoma have on MRI?
SINGLE ring-enhancing lesion instead of multiple that CNS toxoplasmosis has
27
Cryptococcal Meningitis occurs with CD4 count less than?
100
28
What is the leading cause of meningitis in AIDS patients?
Cryptococcal Meningitis
29
Symptoms of Cryptococcal Meningitis opportunistic infection?
Fever, headache, altered mental status
30
Fever, headache, altered mental status
Cryptococcal Meningitis
31
How do you diagnose Cryptococcal Meningitis?
Lumbar puncture with CSF shows elevated opening pressure | - and the cryptococcal antigen is (+)
32
A lumbar puncture with CSF shows elevated opening pressure?
Cryptococcal Meningitis
33
What is a common late complication of AIDS (CD4 < 50)?
Mycobacterium Avium Intracellulare
34
Symptoms of Mycobacterium Avium Intracellulare?
Fever, weight loss, night sweats, lymphadenopathy, abdominal pain
35
Symptoms of Mycobacterium Avium Intracellulare?
Fever, weight loss, night sweats, lymphadenopathy, abdominal pain
36
2 options with reactivation of cytomegalovirus (CMV)?
Retinitis | Colitis
37
CMV retinitis symptoms?
Floats, cut visual field, scotomas (flashing lights)
38
CMV colitis symptoms?
Diarrhea, abdominal pain, weight loss
39
CMV retinitis and colitis symptoms?
CMV retinitis - floaters, cut visual field, scotomas (flashing lights) CMV colitis - diarrhea, abdominal pain, weight loss
40
Candidiasis infection involve what physical exam finding in the mouth?
White plaques that easily scrape off
41
Oral hairy leukoplakia differs from Candidiasis in that?
The white plaques do NOT scrape off | - associated with EBV
42
Prophylaxis for PJP and Toxoplasmosis?
Trimethoprim - Sulfamethoxazole (TMP-SMX)
43
Prophylaxis for PJP and Toxoplasmosis?
Trimethoprim - Sulfamethoxazole (TMP-SMX)
44
Prophylaxis for Pneumocystis Jirovecii Pneumonia and CNS Toxoplasma?
Trimethoprim - Sulfamethoxazole (TMP-SMX)