AIDS - opportunistic infections Flashcards
What is the most common opportunistic infection?
Pneumocystis Jirovecii Pneumonia (PJP)
Symptoms of infection with Pneumocystis Jirovecii Pneumonia?
Fever, non-productive cough, dyspnea, pleuritic chest pain
What is the most common physical exam finding with Pneumocystis Jirovecii Pneumonia?
Exertional Hypoxia
What does a CT scan show with Pneumocystis Jirovecii Pneumonia?
Ground-glass infiltrates in the lungs
Fever, dyspnea, non-productive cough, exertional hypoxia are seen with what opportunistic infection?
Pneumocystis Jirovecii Pneumonia
Ground-glass infiltrates in the lungs will be seen with what opportunistic infection?
Pneumocystis Jirovecii Pneumonia
PJP occurs with CD4 count less than?
200
How do you diagnose PJP?
Bronchoalveolar lavage
Sputum analysis
Mycobacterium Tuberculosis occurs with CD4 count less than?
500
Symptoms of infection with Mycobacterium Tuberculosis?
Fever, cough, dyspnea, weight loss, night sweats
Fever, cough, dyspnea, weight loss, night sweats
Mycobacterium Tuberculosis
What will be present in imaging of the lungs with Mycobacterium Tuberculosis?
Apical cavitary lesion in upper lung fields
Apical cavitary lesion in the upper lung fields will be seen with what opportunistic infection?
Mycobacterium Tuberculosis
What CD4 count is necessary to get Community Acquired Pneumonia?
ANY
Symptoms of Community Acquired Pneumonia?
Fever, cough, shortness of breath, chest infiltrates
2 typical organisms that cause Community Acquired Pneumonia?
Strep. Pneumoniae
H. Influenzae
CNS Toxoplasmosis occurs with a CD4 count less than?
100
What toxoplasma antibody will be (+) in toxoplasmosis?
IgG
How do you get CNS toxoplasmosis?
Reactivation of latent tissue cysts in patients with prior toxoplasmosis infection
Symptoms of CNS Toxoplasmosis?
Fever, headache and FOCAL NEURO DEFICITS
Fever, headache and focal neuro deficits?
CNS Toxoplasmosis
What will be seen on MRI with CNS toxoplasmosis infection?
MULTIPLE ring-enhancing lesions
Primary CNS Lymphoma can present similar to?
CNS toxoplasmosis
Primary CNS lymphoma occurs with a CD4 count less than?
50
Symptoms of Primary CNS lymphoma?
Fever, headache and FOCAL NEURO DEFICITS
Primary CNS lymphoma and CNS Toxoplasmosis have the same symptoms. What does Primary CNS lymphoma have on MRI?
SINGLE ring-enhancing lesion instead of multiple that CNS toxoplasmosis has
Cryptococcal Meningitis occurs with CD4 count less than?
100
What is the leading cause of meningitis in AIDS patients?
Cryptococcal Meningitis
Symptoms of Cryptococcal Meningitis opportunistic infection?
Fever, headache, altered mental status
Fever, headache, altered mental status
Cryptococcal Meningitis
How do you diagnose Cryptococcal Meningitis?
Lumbar puncture with CSF shows elevated opening pressure
- and the cryptococcal antigen is (+)
A lumbar puncture with CSF shows elevated opening pressure?
Cryptococcal Meningitis
What is a common late complication of AIDS (CD4 < 50)?
Mycobacterium Avium Intracellulare
Symptoms of Mycobacterium Avium Intracellulare?
Fever, weight loss, night sweats, lymphadenopathy, abdominal pain
Symptoms of Mycobacterium Avium Intracellulare?
Fever, weight loss, night sweats, lymphadenopathy, abdominal pain
2 options with reactivation of cytomegalovirus (CMV)?
Retinitis
Colitis
CMV retinitis symptoms?
Floats, cut visual field, scotomas (flashing lights)
CMV colitis symptoms?
Diarrhea, abdominal pain, weight loss
CMV retinitis and colitis symptoms?
CMV retinitis - floaters, cut visual field, scotomas (flashing lights)
CMV colitis - diarrhea, abdominal pain, weight loss
Candidiasis infection involve what physical exam finding in the mouth?
White plaques that easily scrape off
Oral hairy leukoplakia differs from Candidiasis in that?
The white plaques do NOT scrape off
- associated with EBV
Prophylaxis for PJP and Toxoplasmosis?
Trimethoprim - Sulfamethoxazole (TMP-SMX)
Prophylaxis for PJP and Toxoplasmosis?
Trimethoprim - Sulfamethoxazole (TMP-SMX)
Prophylaxis for Pneumocystis Jirovecii Pneumonia and CNS Toxoplasma?
Trimethoprim - Sulfamethoxazole (TMP-SMX)