Skin Changes Flashcards
What are 2 viruses that can cause vesicular rashes?
Herpesvirus 1 and 2
Herpes Zoster
Herpes Zoster infection can cause vesicular rashes. What are the 2 types?
Varicella rash
Zoster rash
Describe the Varicella rash seen with Herpes Zoster infection
- Papular
- Vesicular
- Pustule
- Crust
= ALL appear at once
Describe the Zoster rash seen with Herpes Zoster infection
Eruption of vesicles in a dermatomal distribution with pain
What are the symptoms of meningitis?
Fever Headache Stiff neck/back Vomiting and delirium - Petechial rash
Describe the CSF with meningitis
Purulent CSF (+) for Gram (-) intra and extracellular diplococci
What is a possible complication of meningococcal infection?
DIC - purpura fulminans
What is purpura fulminans?
DIC associated skin findings after Meningococcal infection
Seborrheic Keratosis
Brown/Black papules/plaques
- BENIGN
Benign brown/black papules/plaques
Seborrheic Keratosis
Seborrheic Keratosis is common in what age group?
Older adults
Is treatment needed for Seborrheic Keratosis?
NO - may be confused with melanomas
Actinic Keratosis
Pinkish macules/papules that occur on sun-exposed parts of the body
What are the symptoms of Actinic Keratosis?
Pinkish macules/papules that are tender and feel like sandpaper
Actinic Keratosis is considered premalignant. What will you likely develop?
Squamous cell carcinoma
Seborrheic Dermatitis
Dry scales common on scalp, face, eyelids, genitals and skin folds
Dry scales common on scalp, face, eyelids, genitals and skin folds
Seborrheic Dermatitis
What patient population often gets Seborrheic Dermatitis?
Parkinson’s and HIV patients
What is the most common cutaneous malignancy?
Basal cell cutaneous carcinoma
Basal cell cutaneous carcinomas often look like ____ with a history of _____
Pearly papule
- History of bleeding
Squamous cell cutaneous carcinomas often look like ____
Warty nodule
Which has a higher rate of metastasis - basal or squamous cell carcinoma?
Squamous cell cutaneous carcinoma
What types of people are at higher risk for basal cell and squamous cell cutaneous carcinomas?
Fair skinned person with history of sun exposure or organ transplant
Pearly papule with a history of bleeding?
Basal cell cutaneous carcinoma
Warty nodule with a high rate of metastasis?
Squamous cell cutaneous carcinoma
What does a Psoriasis plaque look like?
Salmon-colored, well demarcated plaque with overlying silvery scale
Where do Psoriasis plaques usually reside?
Extensor surfaces - knee, elbow
- Or scalp
Psoriasis is associated with what other syndrome/diseases?
Metabolic syndrome
Cardiovascular disease
What can cause a flare up with Psoriasis?
Cold, dry, hot weather
Stress
Medications
Skin trauma
Malignant Melanoma signs?
ABCDE
- Asymmetry
- Borders - irregular
- Color - multiple
- Diameter - > 6 mm
- Evolution - changing!
What 2 things are the most significant determinant in the prognosis of malignant melanoma?
Color
Tissue depth
Malignant Melanoma signs?
ABCDE
- Asymmetry
- Borders - irregular
- Color - multiple
- Diameter - > 6 mm
- Evolution - changing!
Erythema migrans is often seen with what disease?
Lyme Disease
Lyme Disease often is associated with what lesion?
Erythema Migrans
Describe Erythema Multiforme
- Central redness
- Lighter ring of redness around the center
- Outer ring of redness
- Halo surrounding the entire thing
Erythema Multiforme is often seen with what infections?
Herpes Simplex
Mycoplasma Pneumoniae
Erythema Multiforme is often seen with what infections?
Herpes Simplex
Mycoplasma Pneumoniae
Herpes Simplex and Mycoplasma Pneumoniae often have what lesion?
Erythema Multiforme
What is Dermatomyositis?
Chronic, immune-mediated disorder with periorbital redness and papules over the dorsal knuckles
- itchy, scaly, red patches on scalp as well
What 2 signs are pathognomonic for Dermatomyositis?
Periorbital redness
Papules over the dorsal knuckles
Periorbital redness, papules over dorsal knuckles with itchy, scaly and red patches on the scalp?
Dermatomyositis
Pretibial Myxedema
Pink, waxy, indurated plaque on the shin
With what condition can pretibial myxedema be present?
Hyperthyroidism (grave’s)
- Pink, waxy, indurated plaque on the shin
What is Erythema Nodosum?
Lower extremity subcutaneous nodule
What is Erythema Nodosum associated with?
Sarcoidosis
Symptoms of Scarlet fever?
Red, diffuse, papular “sandpaper rash” with STRAWBERRY TONGUE
Sandpaper rash and strawberry tongue are seen with?
Scarlet Fever
Koplick spots in the mouth and a papular rash are seen with?
Measles
What is the Nikolsky sign?
Lateral pressure on skin causes epidermis to slough off
With what condition is the Nikolsky sign (+)?
Pemphigus Vulgaris
With what condition is the Nikolsky sign (-)?
Bullous Pemphigoid
Bullous pemphigoid
Deep intact blisters that start on the legs and move up
Bullous pemphigoid is ____ and affects ____
Itchy and affects elderly
What causes Bullous Pemphigoid?
Typer 2 hypersensitivity reactions to drugs and UV light
Pemphigus Vulgaris
Large bullae that peel off
Pemphigus Vulgaris is ____
Painful
What causes Pemphigus Vulgaris?
Autoimmune
Large bullae that peel off
Pemphigus Vulgaris
Blisters that are itchy and intact
Bullous pemphigoid
Pemphigus Vulgaris will have a (+)
Nikolsky sign
- lateral pressure on skin causes sloughing of epidermis