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SBL > Complications of Transfusion > Flashcards

Complications of Transfusion Flashcards

1
Q

Red cells are stored at?

A

4 degrees celsius

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2
Q

Plasma cells are stored at?

A

-30 degrees celsius

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3
Q

Platelets are stored at?

A

22 degrees celsius

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4
Q

Based on their storage temperatures, which part of blood products are at the most risk for infection with something?

A

Platelets

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5
Q

Platelets are at the biggest risk to contain infection with?

A

Bacteria

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6
Q

What are signs that a transfusion product contains bacteria?

A

Fever and hypotension during transfusion

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7
Q

3 ways to avoid infected products?

A

Donor screening
Test products for many viruses, syphilis, etc.
Storage conditions

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8
Q

Acute Immune Hemolytic reaction occurs to other blood antigens. What antibody mediates this?

A

IgM

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9
Q

Who can A blood type donate RBC to?

A

A, AB

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10
Q

Who can A blood type donate plasma to?

A

A, O

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11
Q

Plasma contains what type of antibodies that affect who you can donate plasma to?

A

Anti-antigen antibodies
ex. Blood A can donate to any ANTI-B blood group
= A and O

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12
Q

Who can B blood type donate RBC to?

A

B, AB

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13
Q

Who can B blood type donate plasma to?

A

B, O

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14
Q

Who can AB blood type donate RBC to?

A

AB

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15
Q

Who can AB blood type donate plasma to?

A

A, B, AB, O

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16
Q

Universal donor of blood?

A

O

17
Q

Delayed Immune Hemolytic reaction occurs with Rh- mothers and their second Rh+ child. What antibody mediates this response?

A

IgG

18
Q

Mothers who are Rh-, after their second Rh+ child, contain what type of antibodies?

A

Anti-D (Rh)

19
Q

If transfusion of red cells causes an anaphylactic reaction, what should be suspected?

A

IgA deficiency

20
Q

What prevents Transfusion - related anaphylaxis with IgA deficiency?

A

Red cell washing

21
Q

2 transfusion related phenomena?

A

TRALI - acute lung injury

TRIM - immune modulation

22
Q

What is TRALI (acute lung injury)?

A

Acute respiratory failure during/after transfusion

23
Q

Acute respiratory failure during/after transfusion

A

TRALI

24
Q

Physical findings with TRALI (acute lung injury)?

A

Bilateral diffuse pulmonary infiltrates
Fever
Hypotension
- possibly fatal

25
Q

What is TRIM (immune modulation)?

A

Pro-inflammatory response and immune downregulation after transfusion

26
Q

Pro-inflammatory response and immune downregulation after transfusion

A

TRIM

27
Q

TRALI and TRIM, are they understood?

A

NO

SBL (48 decks)

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