Structure of DNA Flashcards
Experiment proving genetic material between two strains?
Draw out Fredrick Griffith’s experiment, transformative
Experiment that concludes what molecules carry genetic material
Oswald Avery, Colin MacLeod, and Maclyn McCarty created solutions that killed off RNA, DNA, and proteins.
The solution that contained DNA killing enzyme and virulent solution= turned out to be non-virulent
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What is a nucleoside? and what is a nucleotide?
Nucleoside: sugar and a base combines
Nucleotide: sugar, base, and a phosphate group
Who modeled the structure of DNA
Watson and cricket : DNA structure
Rosalind Franklin: X-ray crystallography
Ewerin chagaff: equal amount of purines to pyramidines
John griffith: the pairing of bases
Key structural features of DNA
- DNA is made up of subunits called nucleotides
- DNA is linked by phosphodiester bonds
- DNA forms in a double helix
Explain the role of 3 components of a nucleotide
- 5- carbon sugar and phosphate group : backbone of the molecule
- The base is responsible for giving the nucleotide its identity
Base pairs are … and are paired through
A and T
G and C
Hydrogen bonding through
What aid does phosphider bonds give nucleic acids?
- Gives DNA Polarity
- Can withstand heat and stresses such as change in Ph
DNA bases are
A,T,G,C
RNA bases are
A, U, G, C
Phosphodiester bond is
C-O-P-O-C
a bond that attacked the 3’ end carbon to the 5’ end carbon through a phosphate bonding in between
Watson and cricket discovery
proposed that DNA was a double helox
Avery, Mcleod, McCarty
showed that DNA was the “transforming principle” involved in heditary
Rosalind Franklin
X-ray crystallography showing the 3D helix structure of DNA
Charagiff
Discovered base pairing and the equivalent amounts of DNA and RNA
