Cell membrane Flashcards
Parts that make up the cell membrane
- lipids
- proteins
- carbohydrates
Two parts of phospholipids and their functions
Phosphate head: Hydrophilic, polar, form hydrogen bonds with water
Fatty acid tail: Hydrophobic, nonpolar, no hydrogen bonds
amphipathic molecule
a molecule with both hydrophilic and hydrophobic regions
Draw a lipid with labeled regions
Three shapes of lipids
Micelle: bulky head and one fatty tails
Bilayer: small head two fatty tails
Liposomes: Spherical form of lipids
What conditions affect the lipid bilayer?
- concentration of lipids
- The PH of the cell
- Temperature
How does Van der Waals forces effect lipid mobility?
The more van der Waals forces the less mobile the lipid becomes
How does saturation effect lipids mobility
- The more saturated means more van der Waals forces between hydrogen bonds, so less mobility
- The more saturated means longer fatty acid chains which cause less mobility
Parts of cholesterol
- The hydroxyl group: Hydrophilic
- 4 connected carbon rings with a hydrocarbon chain
How does Cholesterol affect membrane fluidity?
At normal temperature cholesterol decreases fluidity: rings weigh down lipid
At low temperatures, it increases fluidity.
Cholesterol maintains the cell fluidity no drastic shift from solid to liquid
How do proteins serve the cell?
- Transporters
- Receptors
- Enzymes
- Anchors
Two categories for membrane proteins
Integral membrane proteins: are permanently associated with the cell and cannot be separated from the cell without destroying it.
Peripheral membrane proteins: are temporarily associated with the lipid bilayer through weak covalent bonds
Role of integral membrane proteins:
Transmembrane Proteins span the entire lipid bilayer.
- interacts with signaling molecules
- Interacts with the proteins in the cytoplasm
(Draw out the regions )
Experimental proof that proteins move through the cell membrane
Experiment: Fluorescence recovery after bleach is a process where a small area of the cell membrane is bleached while the proteins are dyed. If the bleached part becomes dyed then the proteins traveled there. That is what happened.