STEROIDS Flashcards
Addisons disease
destruction of adrenal tissue
Cushings disease
excess adrenal action
therapeutic corticosteroids use
for suppression of adrenal action and steroid adverse effects
reduces inflammation
immunosuppression
what hormone regulates blood pressure by managing sodium and potassium levels in blood
aldosterone
what produces aldosterone
adrenal gland
what drugs inhibit the action of aldosterone
ACE inhibitors
AT2 blockers
what steroid hormone is produced by both adrenal glands
cortisol
what does cortisol do
fat and protein breakdown
inhibits bone synthesis
most common therapeutic corticosteroid
prednisolone
what corticosteroid is prescribed for topical management of oral mucosal inflammation
betamethasone
what steroids are used to treat adrenal hyperfunction (cushings)
glucocorticoids
primary adrenal hyperfunction
adrenal tumour
secondary adrenal hyperfunction
pituitary tumour
cause of cushings syndrome
excess cortisol
cushings syndrome symptoms
poor resistance to infection
back pain and bone fractures
psychiatric disorders
skin and mucosal pigmentation
infertility
cushings syndrome signs
centripetal obesity - moon face and hump
hypertension
thin skin and purpura
muscle weakness
osteoporotic changes and fractures
primary adrenal hypofunction
addisons disease
secondary adrenal hypofunction
pituitary failure
cause of addisons disease
autoimmune gland destruction due to infection and infarction
pituitary failure causes
compression from other adenoma
addisons disease signs
postural hypotension
weight loss and lethargy
hyperpigmentation
vitiligo
what is the cause of hyperpigmentation
increased ACTH secretion
addisons disease symptoms
weakness
anorexia
loss of body hair (females)
common dental aspect of cushings
candidiasis
common dental aspect of addisons and cushings
oral pigmentation
