STEROIDS Flashcards

1
Q

Addisons disease

A

destruction of adrenal tissue

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2
Q

Cushings disease

A

excess adrenal action

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3
Q

therapeutic corticosteroids use

A

for suppression of adrenal action and steroid adverse effects
reduces inflammation
immunosuppression

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4
Q

what hormone regulates blood pressure by managing sodium and potassium levels in blood

A

aldosterone

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5
Q

what produces aldosterone

A

adrenal gland

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6
Q

what drugs inhibit the action of aldosterone

A

ACE inhibitors
AT2 blockers

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7
Q

what steroid hormone is produced by both adrenal glands

A

cortisol

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8
Q

what does cortisol do

A

fat and protein breakdown
inhibits bone synthesis

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9
Q

most common therapeutic corticosteroid

A

prednisolone

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10
Q

what corticosteroid is prescribed for topical management of oral mucosal inflammation

A

betamethasone

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11
Q

what steroids are used to treat adrenal hyperfunction (cushings)

A

glucocorticoids

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12
Q

primary adrenal hyperfunction

A

adrenal tumour

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13
Q

secondary adrenal hyperfunction

A

pituitary tumour

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14
Q

cause of cushings syndrome

A

excess cortisol

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15
Q

cushings syndrome symptoms

A

poor resistance to infection
back pain and bone fractures
psychiatric disorders
skin and mucosal pigmentation
infertility

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16
Q

cushings syndrome signs

A

centripetal obesity - moon face and hump
hypertension
thin skin and purpura
muscle weakness
osteoporotic changes and fractures

17
Q

primary adrenal hypofunction

A

addisons disease

18
Q

secondary adrenal hypofunction

A

pituitary failure

19
Q

cause of addisons disease

A

autoimmune gland destruction due to infection and infarction

20
Q

pituitary failure causes

A

compression from other adenoma

21
Q

addisons disease signs

A

postural hypotension
weight loss and lethargy
hyperpigmentation
vitiligo

22
Q

what is the cause of hyperpigmentation

A

increased ACTH secretion

23
Q

addisons disease symptoms

A

weakness
anorexia
loss of body hair (females)

24
Q

common dental aspect of cushings

A

candidiasis

25
Q

common dental aspect of addisons and cushings

A

oral pigmentation