ACUTE CORONARY SYNDROMES Flashcards
Angina symptoms
tightness/ crushing feeling in chest
Angina cause
Narrowing of coronary arteries so require more O2 from cardiac muscle
Diseases that precipitate angina
Anaemia
Hyperthyroidism
Angina investigations
Exercise ECG
Angiography
Echocardiography
Radioisotope studies
Aim of angina tx
reduce O2 demand of the heart - reduce BP afterload, preload and correct mechanical issues (failing valves, septal defects)
Non-drug angina therapy
Modify risk factors - stop smoking, exercise, improve diet/ control cholesterol
Angina drug therapy
Aspirin
Diuretics
Ca channel antagonists
ACE inhibitors
Beta blockers
Nitrates
Emergency angina tx
GTN spray
Angina surgical therapy
Coronary artery bypass grafting - veins from legs grafted into aorta and carry blood past obstruction
Angioplasty and stenting - canula in leg/arm, balloon stretch artery - antiplatelets prescribed alongside
Peripheral vascular disease
angina of the tissues usually in lower limbs - atheroma in femoral/ popliteal vessels
Peripheral vascular disease symptoms
Pain/ anaerobic cramp in limb on exercise
Relived with rest
Poor wound healing
Potential necrosis
Myocardial infarction cause
Blood clotting in arteries due to atherosclerosis = no blood flow to area so tissue necroses
Types of infarctions
heart - coronary artery atheroma
limb - femoral and popliteal arteries
brain - carotid arteries; embolic stroke
MI management
thrombolysis and angioplasty - dissolves clot
CABG, fem/pop bypass - bypass obstruction
risk factor management and aspirin - prevent further episode
Carotid artery atherosclerosis results in?
ischaemic stroke
MI diagnosis is found through
ECG findings; STEMI, NSTEMI
Biomarker Troponin
STEMI vs NSTEMI
STEMI - classic heart attack
NSTEMI - blockage of small artery or partial blockage of main artery
Primary care for MI
Analgesia, aspirin
BLS
Hospital tx for MI
Acute angioplasty and stenting (up to 3 hours from onset)
Thrombolysis (up to 6 hours from onset)
Thrombolysis contraindications
Recent blood clots
severe hypertension
active peptic ulcer disease
diabetic eye disease
liver disease
pregnancy
Long term medical management of MI
Prevent next MI - apsirin, B blocker, ACE inhibitor