LEUKAEMIA Flashcards

1
Q

leukaemia

A

cancer of the bone marrow which prevents normal manufacture of the blood

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1
Q

what type of DNA mutation is a haematological malignancy

A

translocation

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2
Q

what does leukaemia result in

A

anaemia
infection
bleeding

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3
Q

neutropenia

A

infection

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4
Q

thrombocytopenia

A

bleeding

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5
Q

what type of infection may present with leukaemia

A

infections associated with portals of entry; mouth, throat, chest, skin, perianal

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6
Q

acute lymphoblastic leukaemia peak age

A

4 years old

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7
Q

acute lymphoblastic leukaemia symptoms

A

catabolic state - fever, sweats, malaise
lymphadenopathy
tissue infiltration

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8
Q

acute myeloid leukaemia age

A

elderly

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9
Q

chronic lymphocytic leukaemia

A

B cell clonal lymphoproliferative disease

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10
Q

chronic myeloid leukaemia age

A

50-70

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11
Q

chronic myeloid leukaemia

A

increase neutrophils and precursors

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12
Q

chronic myeloid leukaemia symptoms

A

fatigue
weight loss
sweating
anaemia
bleeding
splenomegaly

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