BLOOD DISORDERS INTRO Flashcards
5 constituents of blood
cells
plasma proteins
water
nutrients
lipids
3 functions of the blood
transport nutrients
remove waste
transport host defences
plasma proteins in blood
albumin 60%
globulin 35%
fibrinogens 4%
buffer layer of blood
WBC and platelets
full blood count includes
RBC
WCC
PLT
HCT
MCV
low Hb
anaemia
low WCC
Luekopenia
low platelets
thrombocytopenia
all cells reduced
pancytopenia
raised Hb
polycythaemia
raised WCC
Leukocytosis
raised platelets
thrombocythaemia
neoplastic proliferation of white cells, usually disseminated
leukaemia
neoplastic proliferation of white cells, usually a solid tumour
lymphoma
acute lymphoid
acute lymphoblastic leukaemia
acute myeloid
acute myeloid leukaemia
chronic lymphoid
chronic lymphocytic leukaemia
hodgkin lymphoma
non-hodgkin lymphoma
multiple myeloma
chronic myeloid
chronic myeloid leukaemia
myeloproliferative disorders
myeloproliferative disorders
bone marrow makes too many red blood cells, white blood cells, or platelets
abnormality of haem metabolism
porphyria
porphyria main groups
hepatic and erythropoietic
where is haem metabolised
cytoplasm and mitochrondria
porphyria triggers in the dental practise
LA
Hereditary copoporphyria
inherited form of liver porphyria
Hereditary coproporphyria characteristics
episodes (acute attacks) of stomach pain, nausea, vomitting, weakness, numbness, and pain in hands and feet.
variegate porphyria
hepatic form of porphyria
variegate porphyria symtpom
skin sensitivity to sunlight
clinical effects of porphyria
photosensitive rash
neuropsychiatric disturbance in acute attacks
hypertension and tachycardia
may be fatal
