BLOOD DISORDERS INTRO Flashcards

1
Q

5 constituents of blood

A

cells
plasma proteins
water
nutrients
lipids

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2
Q

3 functions of the blood

A

transport nutrients
remove waste
transport host defences

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3
Q

plasma proteins in blood

A

albumin 60%
globulin 35%
fibrinogens 4%

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4
Q

buffer layer of blood

A

WBC and platelets

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5
Q

full blood count includes

A

RBC
WCC
PLT
HCT
MCV

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6
Q

low Hb

A

anaemia

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7
Q

low WCC

A

Luekopenia

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8
Q

low platelets

A

thrombocytopenia

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9
Q

all cells reduced

A

pancytopenia

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10
Q

raised Hb

A

polycythaemia

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11
Q

raised WCC

A

Leukocytosis

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12
Q

raised platelets

A

thrombocythaemia

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13
Q

neoplastic proliferation of white cells, usually disseminated

A

leukaemia

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14
Q

neoplastic proliferation of white cells, usually a solid tumour

A

lymphoma

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15
Q

acute lymphoid

A

acute lymphoblastic leukaemia

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16
Q

acute myeloid

A

acute myeloid leukaemia

17
Q

chronic lymphoid

A

chronic lymphocytic leukaemia
hodgkin lymphoma
non-hodgkin lymphoma
multiple myeloma

18
Q

chronic myeloid

A

chronic myeloid leukaemia
myeloproliferative disorders

19
Q

myeloproliferative disorders

A

bone marrow makes too many red blood cells, white blood cells, or platelets

20
Q

abnormality of haem metabolism

A

porphyria

21
Q

porphyria main groups

A

hepatic and erythropoietic

22
Q

where is haem metabolised

A

cytoplasm and mitochrondria

23
Q

porphyria triggers in the dental practise

A

LA

24
Q

Hereditary copoporphyria

A

inherited form of liver porphyria

25
Q

Hereditary coproporphyria characteristics

A

episodes (acute attacks) of stomach pain, nausea, vomitting, weakness, numbness, and pain in hands and feet.

26
Q

variegate porphyria

A

hepatic form of porphyria

27
Q

variegate porphyria symtpom

A

skin sensitivity to sunlight

28
Q

clinical effects of porphyria

A

photosensitive rash
neuropsychiatric disturbance in acute attacks
hypertension and tachycardia
may be fatal