CONNECTIVE TISSUE DISEASE

Question 1

Name the multisystem vasculitic inflammatory diseases

Answer 1

systemic lupus erythematous (SLE)
systemic sclerosis (scleroderma)
Sjogren’s syndrome (SS)
undifferentiated connective tissue disease (UCTD)

Question 2

types of vasculitic diseases

Answer 2

large vessel disease - giant cell (temporal) arteritis
medium vessel disease - polyarteritis nodosa, kawasaki disease
small vessel disease - wegners granulomatosis

Question 3

general medication for pain

Answer 3

analgesics
NSAIDs

Question 4

immune modulating drugs

Answer 4

hydroxychloroquine
methotrexate
azathioprine
mycophenolate
biologics

Question 5

systemic steroid eg

Answer 5

prednisolone

Question 6

lupus antibodies

Answer 6

ANA
dsDNA
Ro

Question 7

lupus features

Answer 7

butterfly rash on face
lung, heart, kidney problems
arthritis and raynauds

Question 7

what does lupus result in which affects oral ulceration

Answer 7

chronic anaemia

Question 8

what oral effect foes hydroxychloroquine have

Answer 8

pigmentation

Question 9

antiphospholipid antibody syndrome effect

Answer 9

recurrent thrombosis

Question 10

can you stop anticoagulant intake for someone with APS

Answer 10

NO

Question 11

Groups of sjogrens

Answer 11

sicca syndrome
primary sjogrens
secondary sjogrens

Question 12

what type of sjogrens is associated with dry eyes

Answer 12

sicca syndrome

Question 13

what type of sjogrens isnt associated with any other disease

Answer 13

primary

Question 14

what type of sjogrens is associated with another connective tissue disease

Answer 14

secondary

Question 15

systemic sclerosis

Answer 15

excessive collagen deposition, connective tissue fibrosis and loss of elastic tissue

Question 16

local systemic sclerosis antibodies

Answer 16

anticentromere

Question 17

generalised systemic sclerosis antibodies

Answer 17

anti scl-70

Question 17

what disease may systemic sclerosis result in

Answer 17

raynauds
renal failure
malabsorption

Question 18

dental aspects of systemic sclerosis

Answer 18

perioral tissue involvement
SJOGRENS
dysphagia and reflux oesophagitis
widened PDL

Question 19

Vasculitis

Answer 19

inflammation of blood vessels and infarction of tissue

Question 20

how may vasculitis present in the mouth

Answer 20

oral inflammatory masses
ulcers

Question 21

what do pt polymyalgia rheumatica also usually have?

Answer 21

giant cell arteritis - large vessel disease

Question 22

polymyalgia rheumatica presentation

Answer 22

headache/ facial pain
chewing claudication and blindness
muscle morning pain
non-specific systemic features

Question 23

poylmyalgia rheumatica tx

Answer 23

steroids

Question 24

polyarteritis nodosa

Answer 24

medium vessel disease

Question 25

kawasaki disease

Answer 25

polyarteritis nodosa
‘mucocutaneous lymph node syndrome’

Question 26

kawasaki disease presentation

Answer 26

fever
lymphadenopathy
crusting/ cracked tongue
strawberry tongue and red mucosa
peeling rash on hands and feet

Question 27

wegeners granulomatosis

Answer 27

small vessel disease

Question 28

wegeners granulomatosis presention

Answer 28

destruction of hard and soft facial tissues
spongy red tissue

Question 29

wegeners granulomatosis antibodies

Answer 29

ANCA

Question 30

what other systems does wegeners granulomatosis affect

Answer 30

resp
renal

Question 31

fibromyalgia

Answer 31

non-specific collection of musculoskeletal symptoms - pain all over body

Question 32

main tx of vasculidities

Answer 32

steroids